Lorrainegenscript · Newsroom

GenScript Licenses CRISPR/Cas9 gene editing technology from the Broad Institute
GenScript and its affiliates announced today that they have entered into a non-exclusive license agreement with the Broad Institute of MIT and Harvard to strengthen their existing GenCRISPR™ services portfolio.

February 28, 2015

GenScript Awarded $10 Million in Trade Secret Case against GeneWiz Biotech
GenScript USA, Inc. and its affiliated companies recently won a significant jury verdict in a trade secret case against Genewiz Inc.

December 12, 2014

Tumor-killing Guinea Pig enzyme finally characterized, 60 years later
In order to express and purify bacterial and mammalian L-asparaginases for enzymatic and structural assays, these researchers ordered codon-optimized gene synthesis from GenScript.

November 12, 2014

Improving Food Crops while avoiding GMO worries -- is CRISPR the answer?
In an effort to combat vitamin A deficiency, Superbananas are among the latest biofortified plants that have been

August 27, 2014

Ebola Virus: Development of Vaccines and Therapeutic Drugs
The 2014 outbreak of Ebola virus highlights the urgent need to develop an effective vaccine to prevent the spread of this deadly virus, and effective therapies to improve survival rates among those infected with Ebola.

August 22, 2014

Newly identified insulin degradation enzyme inhibitor showed promising anti-diabetic effect
Insulin degradation enzyme (IDE) knockout mice have elevated insulin levels, but exhibited impaired, rather than improved glucose homeostasis.

August 5, 2014

Crystallized Fab/peptide complex could help scientists design a potential hepatitis C vaccine
Expanding on this, the scientists resolved the crystallized structures of two of the antibodies’ Fab region .

August 1, 2014

Childhood leukemia can be reversed by switching on the Pax5 gene
Childhood leukemia can be reversed by switching on the Pax5 gene

July 30, 2014

Targeting Fibroblast Activation Protein in Tumor Stroma
Chimeric antigen receptor (CAR) T-cell therapies are touted as the next generation of highly selective, anti-cancer therapeutics against leukemia, lymphomas, breast cancer and GD2-positive sarcomas.

July 28, 2014

iphone "bionic pancreas" device used in human trial to treat diabetes
Performing fundamental diabetes research or developing diabetes peptide drugs? Try our custom peptide synthesis services.

July 25, 2014

Inhibiting one step of prostaglandin synthesis in macrophages can help manage pain
Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen work by preventing the cyclooxygenase-2 (COX-2) enzyme from producing prostaglandins

June 4, 2014

Calcium sensor STIM2 maintains synapses lost with Alzheimer's disease
How does less calcium entering spines destabilize mature synapses?

May 30, 2014

The synthetic yeast genome project, Sc2.0
is laying the groundwork for a new era of life sciences and biotechnology

May 29, 2014

Twins & TCR repertoires: Can twins help us understand T cell receptor diversity?
What elements of final TCR repertoires are exclusively determined by genetic factors?

May 28, 2014

Novel, Oxygen-induced E. coli expression for high level recombinant protein production
GenScript is a reliable partner for all your protein production projects, regardless of complexity.

May 27, 2014

Top 5 reasons your peptide-based assays fail
One of the most common reasons peptide assays fail is peptide hydrophobicity, which results in peptide insolubility.

May 26, 2014

Start-up company claims peptide-based battery charges smartphone in 30 seconds
Self-assembling peptides are well-known for their use in the creation of hydrogels and other biomaterials in fields such as tissue engineering and regenerative medicine.

May 23, 2014

Delivery of BDNF cDNA into ear boosts cochlear implant performance
A report in Science Translational Medicine finds that electroporation of BDNF into mesenchymal cells of the ear stimulates spiral ganglion neurite regeneration, which improves sensitivity to electrical signals transmitted by cochlear implants.

May 22, 2014

Sunitinib treated dendritic cells increase cytokine induced killer cells' anti-tumor cytotoxicity
Studies suggest that co-culturing cytokine induced killer (CIK) cells with dendritic cells (DC) augments CIK cells' tumor cytotoxicity.

May 21, 2014

Fatal outcome in human trial could have been avoided using new mouse model
A ground breaking study published in PLOS Medicine, describes a mouse model with a humanized liver used for detecting hepatic drug toxicity prior to human testing.

May 20, 2014

Adding N-terminal and C-terminal epitope tags optimizes full length protein purification
In a recent scientific video journal, a group of scientists demonstrated a double-tagging affinity purification technique that allowed the recovery of highly purified, full length target protein.

May 14, 2014

Think twice when you start a biosimilar project
Use of monoclonal antibody drugs is a significant event in the history of medicine.

May 13, 2014

A newly identified post-translational modification critical for learning
Synaptic plasticity is known to underlie learning and memory, but we're still discovering the molecular mechanisms by which synaptic activity leads to changes in synapse morphology and function.

May 12, 2014

New Approach for Immunoprecipitation ,update your protocol with GenScript MagBeads
Traditional immunoprecipitation (IP) uses agarose beads coated in protein A/G and requires at least three washing steps to eliminate background and non-specific binding.

May 9, 2014

REST serves as a reliable predictor of Alzheimer's disease and other aging-related dementias
Alzheimer's disease (AD) is undoubtedly one of the biggest scientific mysteries of the medical world. What is a reliable indicator of this disease?

May 8, 2014

Top 5 reasons why molecular cloning can fail
The purity and concentration of your starting materials are essential for successful cloning.

May 6, 2014

Injecting stem cells directly to heart is effective in treating ischemic heart disease in humans
A new clinical trial demonstrates that injection of stem cells found in bone marrow directly into the heart muscle of patients with severe ischemic heart disease improves heart function.

April 30, 2014

Trastuzumab activates NK cells for increased cytotoxicity
A recent study in the Journal of Clinical Investigation demonstrates that NK cells became activated and express high levels of CD137 following their interaction with trastuzumab coated breast cancer cells.

April 28, 2014

Stimulation of angiogenesis through Notch signaling reverses bone loss
Angiogenesis in bone and osteogenesis seem to be coupled.

April 25, 2014

CRISPR enables heritable multiplex genome editing in insects
CRISPR/Cas9 technology for precise gene editing has already proven successful in mice, C. elegans, Xenopus tropicalis, and plants. Now CRISPR has been used the silkmoth Bombyx mori, an important insect model organism.

April 24, 2014

Plasmid titration can be a valuable technique for the optimization
While DNA-mediated transient transfection of mammalian cells is a widely-used method for recombinant protein production, it is not clear as to what the optimal concentration of DNA should be.

April 23, 2014

Stuck with a dead-end construct with no soluble protein?
Do you spend a lot of time, effort and resources in trying to optimize protein expression conditions?

April 22, 2014

Dual action "stapled peptide" inhibits tumor growth
In a recent study, a new type of peptide drug, called a stapled peptide, was designed as a dual inhibitor of both MDM2 and MDMX, which are inhibitors of the p53 tumor suppressor.

April 21, 2014

His Tag Antibodies from GenScript
Due to its small size, low interference in protein folding and weak immunogenicity, His tag is the most commonly used tag in recombinant protein expression.

April 18, 2014

Bacteria engineered to produce magnetic nanocrystals
In 1963 scientists first reported the existence of bacteria that swim toward the North Pole.

April 17, 2014

Two step, "end-to-end" affinity chromatography
The development of an efficient protocol for recombinant protein purification is a prerequisite for the biochemical and structural characterization of proteins.

April 16, 2014

Investigation finds misconduct in publications
Fast-growing fields, such as stem cell, demand a quickly available and customizable pool of antibodies to avoid needless bottlenecks in research.

April 15, 2014

New compounds inhibit tumor angiogenesis through potent autophagy activation
Two recent studies demonstrate that natural activators of autophagy (Ery5 and convallatoxin) inhibit angiogenesis.

April 14, 2014

New peptide facilitates synaptic transmission, enhances memory in vivo
In a study published in Neuron, researchers discovered a pathway that plays a fundamental role in learning and memory, and designed small interfering peptides to improve cognitive performance relating to memory in vivo.

April 11, 2014

Therapeutic suppression of metastatic melanoma results from transcriptional induction of ApoE
Therapeutic suppression of metastatic melanoma results from transcriptional induction of ApoE

April 10, 2014

GenScript Launches GenEZ™ Next-Generation Molecular Cloning Service
GenScript, the world’s largest provider of synthetic genes, has launched a new GenEZ™ Next-Generation Molecular Cloning service, which reduces the hands-on time that researchers spend on cloning to less than 30 minutes.

April 8, 2014

New opsins Chronos and Chrimson solve the problem
"Optogenetics" allow researchers to stimulate synaptic activity in specific neurons that are made to express light-sensitive

April 4, 2014

How do viruses and nanoparticle delivery vehicles get into cells?
New "viral video" captures approach and attachment of viral-like particles to live cells

April 2, 2014

Neutrophil-dendritic cell hybrids and their role in the immune response
Recent studies have demonstrated that a unique subset of neutrophils expressing MHC II and dendritic cell surface markers are present at various sites of inflammation in the skin, lungs and lymph nodes.

April 1, 2014

Diverse GPCR Cell Lines Ready for Screening
G protein-coupled receptors (GPCRs) constitute a large protein family of receptors that interact with molecules outside the cell and activate intracellular signal transduction pathways.

March 31, 2014

Breaking News: Carriers of a loss-of-function mutation for ZnT8
A new study in Nature Genetics* shows, for the first time, that a loss-of-function mutation may be beneficial in preventing type 2 diabetes (T2D).

March 28, 2014

New mutations discovered in the MC4R "obesity gene"
A recent study on the genetics of obesity found novel variants in the MC4R gene promoter region in a population of obese children.

March 26, 2014

New class of non-β-lactam antibiotics to treat methicillin-resistant Staphylococcus aureus (MRSA)
A team of scientists have discovered a new class of antibiotics with 100% oral bioavailability to fight drug-resistant bacteria including MRSA

March 25, 2014

10% off on our best-selling bacterial protein production packages
Cost and resource constraints in producing proteins in-house compel scientists to offshore their projects.

March 24, 2014

Soon cancer and cardiovascular disease detection could be as simple as taking a pregnancy-like test
In a recent study, published in PNAS, researchers developed an ingenious point-of-care diagnostic method using synthetic peptide biomarkers and immunoassays.

March 21, 2014

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