Lately, there has been huge media interest about vitamin E supplementation - it's safety and benefits. The interest has been mostly driven by journal of two documents in health-related science publications over last months which claimed possible undesirable health effects of vitamin E supplementation. In the conclusion, health professionals and other experts have been flooded with inquiries from their patients about vitamin E and sales of vitamin E supplements have plummeted.

What is the scientific basis of the claims of benefits and harms conveyed by vitamin E supplements?

Why Vitamin E Supplements are Popular

During the past two decades, a number of scientists have suggested a so-called oxidant theory of disease. This theory confronts that oxidative metabolism, and the free radicals that appear from it, is the primary pathophysiologic mechanism underlying a number of serious degenerative diseases such as cancer and cardiovascular disease. This hypothesis, in addition estimates that sufficient, or even big doses of anti-oxidant vitamins such as vitamins C and E, the carotenoids and selenium can protect against such damage. Within all of these potential benefits, the likely protective effects against cardiovascular disease and cancer have been the two most thoroughly processed to the test of randomized clinical trials.

How Widely Used is the Use of Vitamin E Supplements?

The daily use of vitamin supplements, and in particular vitamin E, has evolved to be a extensive routine. Many studies conducted in the past six years have seen ordinary intake (more than 5 times/week) within 25-50% of the adult population and, in practically all cases, the occurrence incrementally raises by age and with the occurrence of chronic degenerative diseases. Normally, these adults have daily doses of 400 mg or more. Even with doctors, vitamin E supplementation for their individual intake is an increasing process.

A Viewpoint on the Doses Including in Vitamin E Supplements

The rising popularity of vitamin E as a valuable nutritional supplement has been drastically improved by the clear safety of the vitamin, with upper limits of safe consumption set by the National Academy of Sciences at 1000 mg/day, or roughly seventy times the advised daily allowance (RDA) for the vitamin. So, while the most typically used dosage for single-nutrient vitamin E supplements is 400 mg or roughly 30-fold greater than the RDA, that degree of supplementation is even so less than half the proposed upper limit of safe consumption.

With such a broad variety of benefits and with an obvious and strong margin of safety, it is not unusual that large groups of the public, as well as health authorities, have obtained the same beliefs uttered lately by a well known heart researcher, who said regarding high dose vitamin E: "It can't hurt and may possibly help, so why not have it?".

Big, scientific studies posted in the second part of the 1980s and early 1990s persistently observed a strong connection between regular vitamin E consumption and the risk of coronary heart disease, with risk cutback of 30 to 60 percent. These reports confirmed an incredibly strong declination in risk connected primarily with the use of high doses of vitamin E but substantially poor results of low dosages of the vitamin.

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