The global CAR T cell therapy market is estimated to grow at a CAGR of nearly 48% during the forecast period. The major factors contributing to the growth of the market include a significant prevalence of cancer across the globe and rising FDA approvals for cell and gene therapy. As per the World Health Organization (WHO), the global cancer burden is estimated to have risen to 18.1 million new cases and 9.6 million deaths in 2018. There were 43.8 million persons living with cancer in 2018 who were diagnosed within the last 5 years. This rising prevalence of cancer is attributing to the development of CAR T cell therapy. It is a form of immunotherapy that utilizes specially altered T cells, a part of the immune system to attack cancer.

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There are currently two CAR T cell therapies approved for the treatment of cancer, which includes Yescarta and Kymriah. Yescarta was approved by the US FDA in October 2017, for the treatment of diffuse large B-cell lymphoma (DLBCL). Kymriah was approved by the US FDA in May 2018, for the treatment of adults with certain kinds of non-Hodgkin lymphoma. Kymriah is also approved for the treatment of children and young adults with leukemia. In clinical trials, more than 80% of young adults and children treated with Kymriah achieved cancer remission.

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Global CAR T Cell Therapy Market Segmentation

By Application

Non-Hodgkin Lymphoma

Acute Lymphocytic Leukemia

Others (Multiple Myeloma, Hodgkin Lymphoma, and Breast Cancer)

By Target Antigen

CD19

CD22

Others (CD123, CD33, and BCMA)

Regional Analysis

North America

United States

Canada

Europe

UK

Germany

Italy

Spain

France

Rest of Europe

Asia-Pacific

China

India

Japan

Rest of Asia-Pacific

Rest of the World

Company Profiles

Amgen Inc.

Autolus Therapeutics plc

bluebird bio, Inc.

Bristol-Myers Squibb Co.

CARsgen Therapeutics Co., Ltd.

Cellectis SA

Celyad SA

Gilead Sciences, Inc.

Intellia Therapeutics, Inc.

Janssen Global Services, LLC (a Subsidiary of Johnson & Johnson)

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