The global circulating tumor cell market size is expected to reach around USD 23.9 billion by 2027 at a CAGR of 13.2% over the forecast period, according to a new report by Grand View Research, Inc. The growth in cancer-related spending for the introduction of companion diagnostics and targeted therapies has driven the circulating tumor cell (CTC) market over the past years. Research organizations are engaged in endeavors aimed at developing circulating tumor cells based tests to improve cancer diagnosis in terms of efficiency and speed.
Furthermore, the growing demand for minimally invasive diagnostic procedures is anticipated to propel investments by key stakeholders in this area. Circulating tumor cell based liquid biopsy tests lead to limited trauma and enable rapid recovery owing to their non-invasive nature. Moreover, it enables minimal invasive screening of tumors before opting for complex surgical procedures, such as radiotherapy, chemotherapy, and surgical removal of tumors, thus positively impacting the adoption.
The limited applicability of these cells in rare cancers has hampered the revenue growth up to a certain extent. For instance, there is a negligible evidence for the characterization of circulating tumor cells for sarcoma. Conversely, several methods are being investigated for isolation of these cells, such as methods based on epithelial antigen-targeted antibodies, which are anticipated to help overcome these challenges in the coming years.
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Further key findings from the report suggest:
• CTC detection and enrichment methods accounted for the largest revenue share owing to the presence of wide availability of products for CTC enrichment and isolation
• Moreover, high penetration in terms of usage of products offered under this segment has driven the segment share
• Growing application of nanomaterials in cancer management is anticipated to drive revenue for direct detection methods in the coming years
• Devices and systems dominated the revenue share in 2019 over its counterpart segments including kits and reagents and blood collection tubes
• Presence of high-throughput automated systems coupled with the availability of a substantial number of systems to carry out detection of tumor cells has contributed to large revenue share
• CTC analysis has major applications in research settings, including investigational research, drug developments, and biomarker studies. This has resulted in a segment’s large revenue share
• Currently, whole blood specimens are the key source of CTCs, thus accounting for the largest share in 2019
• Low use of bone marrow-derived cells in clinical settings has contributed to a smaller revenue share of this segment
• Other sources include CSF, spinal fluids, urine, and pleural effusion
• Easy availability of biological specimens, such as urine, is likely to accelerate adoption under this segment
• The CTC market is fragmented in nature with the presence of well-established players, along with medium to small-sized players
• Some players operating in the space are QIAGEN; Greiner Bio One International GmbH; Menarini Silicon Biosystems; Sysmex Corporation; Bio-Techne Corporation; and Biocept, Inc.
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Grand View Research has segmented the global circulating tumor cell market on the basis of technology, application, product, specimen, and region:
CTC Technology Outlook (Revenue, USD Million, 2016 - 2027)
• CTC Detection & Enrichment Methods
o Immunocapture (Label-based)
o Positive Selection
o Negative Selection
o Size-based Separation (Label-free)
o Membrane-based
o Microfluidic-based
o Density-based Separation (Label-free)
o Combined Methods
• CTC Direct Detection Methods
o SERS
o Microscopy
o Others
• CTC Analysis
CTC Application Outlook (Revenue, USD Million, 2016 - 2027)
• Clinical/Liquid Biopsy
o Risk Assessment
o Screening and Monitoring
• Research
o Cancer Stem Cell & Tumorigenesis Research
o Drug/Therapy Development
CTC Product Outlook (Revenue, USD Million, 2016 - 2027)
• Kits & Reagents
• Blood Collection Tubes
• Devices or Systems
CTC Specimen Outlook (Revenue, USD Million, 2016 - 2027)
• Blood
• Bone Marrow
• Other Body Fluids
CTC Regional Outlook (Revenue, USD Million, 2016 - 2027)
• North America
o U.S.
o Canada
• Europe
o Germany
o U.K.
o France
o Spain
o Italy
• Asia Pacific
o China
o Japan
o India
o South Korea
o Singapore
o Australia
• Latin America
o Brazil
o Argentina
• Middle East & Africa
o South Africa
o UAE
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About Grand View Research
Grand View Research provides syndicated as well as customized research reports and consulting services on 46 industries across 25 major countries worldwide. This U.S.-based market research and consulting company is registered in California and headquartered in San Francisco. Comprising over 425 analysts and consultants, the company adds 1200+ market research reports to its extensive database each year. Supported by an interactive market intelligence platform, the team at Grand View Research guides Fortune 500 companies and prominent academic institutes in comprehending the global and regional business environment and carefully identifying future opportunities.