The experiments showed that a combination treatment of alctinib with either erlotinib or osimertinib -- two existing EGFR-inibiting drugs -- prevented the progression of CNS metastasis, controlling the condition for over 30 days.
Two new medications commonly used to treat type 2 diabetes are similar in their ability to reduce major heart complications, including heart attack, stroke and death from cardiovascular disease.
Researchers discovered that a class of metallodrugs currently used in the treatment of other infectious diseases is showing efficacy to potently suppress SARS-CoV-2 replication and relieve viral-associated symptoms in an animal model.
Larotrectinib (Vitrakvi; Loxo Oncology), the first drug approved for the treatment of adults and pediatric patients with solid tumors that have an NTRK gene fusion without a known acquired resistance mutation