Opioid drugs act on the opioid receptors present in the central and peripheral nervous system. The drug class primarily used in relieving pain includes natural, semi-synthetic, and synthetic opioids. Codeine, morphine, hydrocodone, oxycodone, heroin, and fentanyl are some of the major prescription drugs in the global opioids agonist drugs market. Opioids can be administered as oral pills, parenteral, liquids, patches, or lozenges. Overdose and drug abuse is a major concern for health regulators worldwide, with the situation especially alarming in developed regions with easy access to these drugs. According to the World Drug Report 2016, a staggering 17.4 million people were affected by opioid drug abuse. Drug and health regulators are therefore, taking initiatives to govern pain prescriptions and curb the rate of opioid abuse. The U.S. FDA considers all opioids as schedule 2 drugs—drugs that have high abuse potential. In 2016, the CDC issued guidelines to prescribe opioids, limiting the daily dose of opioids to 90 morphine milligram equivalent (MME). The Global Opioids Agonist Drugs Market was valued at US$ 17,132.5 million in 2015 and is expected to witness a moderate CAGR of 4.2% during the forecast period (2016 – 2024).

Market Dynamics

According to the National Institutes of Health (NIH) estimates published in 2015 by the American Pain Society, nearly 50 million people in the U.S. suffered from chronic pain. Use of opioids in cancer pain, orthopedic pain, neuropathic pain, post-operative pain, and lower back pain is very effective. With growing incidence of chronic pain, demand for opioids will also increase consequently.

North America is the largest market for opioids owing to availability of branded prescription and local products, which inadvertently also leads to drug abuse. There are local unbranded products available for every opioid derivative complementing the available prescription opioid brand. The Centers for Disease Control and Prevention (CDC) states that 73% of all drug overdose deaths in the U.S. in 2015 were due to opioids (57% in 2010). Moreover, emergence of cannabis as an alternative to opioids and legalization of the same in various regions is inhibiting the opioids market growth.

Detailed Segmentation:

Global Opioids Agonist Drugs Market, By Product Type:

Codeine

Fentanyl

Meperidine

Methadone

Morphine

Hydrocodone

Global Opioids Agonist Drugs Market, By Therapeutic Application:

Pain Management

Neuropathic Pain

Migraine

Back Pain

Osteoarthritis Pain

Cancer Pain

Others

Cough Treatment

Diarrhea Treatment

Increasing prevalence of chronic pain is expected to drive the opioids market growth

According to the American Academy of Pain Medicine (2011), the number of people who suffered from chronic pain was around 1.8 billion. Moreover, according to the NIH estimates (2015), one in 10 people in the U.S. suffer from chronic pain. Around one-third to half of the population in the U.K. suffers from chronic pain, according to a study published in the British Medical Journal in 2016. Opioids are commonly used for treating pain, and opioid containing drugs are being misused or are being consumed in overdose when patients follow self-medication. Moreover, rising prevalence of pain, cough and, diarrhea are other factors driving growth of the opioids agonist drugs market. The highly prescribed opioid in the U.S. is hydrocodone.

Key companies covered as a part of this study include Purdue Pharma L.P., Janssen Pharmaceuticals, Inc., West - Ward Pharmaceuticals Corporation, Pfizer, Inc., Egalet Corporation, Allergan plc, Sanofi SA, Boehringer Ingelheim, and Sun Pharmaceutical Industries Ltd.

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In recent times, cannabis has emerged as a potential alternative for opioids. Cannabis is legalized in many states in the U.S. as it is considered safer than opioids. U.S. being a major consumer of such drugs, legalizing cannabis (marijuana) is expected to have a detrimental impact on the opioids market growth.

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