3rd May 2014, USA(http://www.acedrugstore.com/) : It is a medical condition in which a woman is not able to get pregnant within one year after having sexual intercourse even when a couple is not using contraception. Sub-fertility could be possible due to problems in male fertility or women’s fertility. Usually, male sub-fertility is possible due to low sperm count, poor sperm motility, or abnormal forms. Causes of male sub-fertility are:

1.Varicocele

2.Consumption of drugs, alcohol, and smoking cigarettes

3.Idiopathic

4.Anti-sperm antibodies (autoimmune), which is common after vasectomies

5.Kallman syndrome (hypothalamus), not releasing GNrH.

6.Hypopituitarism, which stops releasing LS and/or FSH.

Causes of female sub-fertility could be due to ovulation disturbances, where female is not able to make LS and/or FSH. Similarly, this happens with those women who are obese or thin.

Hyperprolactinaemia, where a high levels of prolactin is caused due to a tumor near the pituitary. It will also lead to amenorrhea, along with headache and other brain tumor symptoms.

Hypogonadal hypogonadism, caused by the problems with pituitary which leads to a lack of LS and/or FSH production.

Tubular disturbances can lead to sub-fertility where a patient has history of pelvic infection which is caused either by TB, or STDs, or if a patient has endometriosis or peritonitis.

Polycystic ovary syndrome is the common cause anovulatory infertility, which is usually present in 20-35 year old and obesity people.

Anxiety could be the reason that can lead to sub-fertility in women. This is possible when women is affected by amenorrhea takes too much stress which results to unwanted weight gain.

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