1. The ability of Basic Copper Carbonate to kill pathogens varies with the change of water environment. Generally speaking, its toxicity increases with the increase of temperature and decreases with the increase of pH value, the increase of organic matter and the presence of salt. Therefore, the dosage should be flexibly controlled according to the specific conditions of the water environment.

2. Excessive basic copper chloride will cause renal tissue necrosis, hematopoietic tissue destruction, and liver fat increase in fish. At the same time, it may remain in gills, muscles, and liver of fish, hindering intestinal absorption, thus affecting food intake and growth of fish. Therefore, it cannot be used frequently.

3. The safe concentration range of Basic Copper Chloride is small. In general use, the basic copper chloride with a concentration of 0.5 ppm to 0.7 ppm is splashed in the whole pool or soaked in the basic copper chloride with a concentration of 8ppm for 20 minutes to 30 minutes. Therefore, it is necessary to accurately measure the volume of aquaculture water and correctly calculate the dosage.