Arimidex (Anastrozole ) is the aromatase inhibitor of choice. The drug is appropriately used when using substantial amounts of aromatizing steroids, or when one is prone to gynecomastia and using moderate amounts of such steroids. Arimidex does not have the side effects of aminoglutheride and can achieve a high degree of estrogen blockade, much moreso than aminoglutheride . It is possible to reduce estrogen too much with Arimidex, and for this reason blood tests , or less preferably salivary tests, should be taken after the first week of use to determine if the dosing is correct.
As an aromatase inhibitor, Arimidex’s mechanism of action — blocking conversion of aromatizable steroids to estrogen — is in contrast to the mechanism of action of anti-estrogens such as Clomid or Nolvadex , which block estrogen receptors in some tissues, and activate estrogen receptors in others. During a cycle, if using Arimidex, there is generally no need to use Clomid as well, but (as mentioned in the section on Clomid there may still be benefits to doing so.
Provironum 25mg [Mesterolone 25mg] – 50 Tabs – Bayer-Shering
Proviron acts as an anti-aromatic: it prevents the aromatization (conversion) of anabolic steroids into estrogen. It avoids gynecomastia and can be combined with Nolvadex to increase its effectiveness. It is indeed clear that Proviron and Nolvadex are both anti-estrogens whose mechanisms of action are different and complementary, and that’s why the combination of these two products is so effective: while Proviron prevents aromatization of anabolics, Nolvadex blocks the estrogen receptor cells, preventing them from acting. It is therefore a formidable tandem.
Proviron is not only an excellent anti-estrogen : Maintaining a low level of estrogen, Proviron also reduces water retention. It gives the user the ripped look sought by many bodybuilders, especially when preparing for competitions.
It should be noted that Proviron tends to limit muscle gains due to a steroid cycle since it attaches to androgen receptor cells instead of other steroids in the body, which are then blocked out and therefore ineffective. This is why many bodybuilders take a minimal dose of Proviron, just to avoid gynecomastia.
Regarding the side effects of mesterolone, they are rare below 100 mg per day. Indeed, tablets of Proviron are not alpha-alkylated 17 and create no harm to the liver. But if we start to exceed the 75 to 100 mg daily, frequently emerging phenomena such as priapism (painful situation in which the penis after erection does not regain its normal flaccidity) in men or virilization in women.
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