In the quest to find relief from chronic migraine headaches, patients will try just about anything. After all, migraines are painful, debilitating headaches. People with chronic migraines experience these severe headaches 15 or more days each month. Quality of life is greatly affected by this disorder. Treatment is the only chance for relief.
Chronic migraine treatment can help ease symptoms, but not all patients respond well to pain medicines. In some cases, doctors prescribe preventive medicines. These are designed to reduce the frequency and severity of headaches. According to a study in the journal Neurology, about one-third of patients with chronic migraines take preventive medicines.
Earlier this decade, onabotulinumtoxinA (more commonly known as Botox-A or Botox) gained U.S. Food and Drug Administration (FDA) approval as a migraine treatment. It is now widely used as a chronic migraine treatment.

How Botox Treats Migraines

Botox treatments for migraines are typically given once every three months. Treatments span a 15-month period. To perform the treatment, your doctor will inject multiple doses of the medicine in specific points along the bridge of the nose, the temples, the forehead, the back of the head, the neck, and the upper back.
The goal of these injections is to reduce the symptoms caused by a migraine headache. These symptoms include nausea; vomiting; and sensitivity to lights, sounds, and smells.
Relief doesn’t happen right away. Improvement can take as long as 10 to 14 days. Some people may not experience any relief with their first set of injections. Additional treatments are sometimes more successful, according to the American Headache Society.

What To Expect From Treatment
Whether you're considering BOTOX® treatment, or have already received treatment, here's what you need to know.
Your first treatment
For Chronic Migraine patients, the FDA has approved a specific dose and injection pattern for BOTOX® treatment—31 injections are given over 7 key areas of the head and neck once every 12 weeks to prevent headache days.¹
Here's what to expect during your first treatment:
• Injections to 7 key areas of the head and neck¹
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• Very fine needles are used for 31 total injections
• Injections feel like tiny pinpricks—you may feel mild discomfort
• The most common side effect in Chronic Migraine clinical studies was neck pain experienced by 9% of BOTOX® patients (vs 3% in placebo)¹
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• Other side effects include headache, migraine, slight or partial facial paralysis, eyelid drooping, bronchitis, musculoskeletal stiffness, muscle weakness, pain in 1 or more muscles, ligaments, tendons, or bones, muscle spasms, injection-site pain, and high blood pressure
• This does not cover all the possible serious side effects of BOTOX®. Please see the Important Safety Information including Boxed Warning and Medication Guide and talk to your doctor

When to expect results
In clinical trials, BOTOX® provided a significant reduction in headache days after the first treatment. After the second treatment (at 24 weeks), BOTOX® prevented up to 9 headache days a month (vs up to 7 with placebo injection).
Why commit to 2 treatments?
Committing to 2 treatment sessions is important in order to see how BOTOX® is working for you, since BOTOX® showed significant reduction in headache days at 24 weeks. Talk to your doctor about your progress, and as you start to see changes in the amount of headache days you’re having each month, keep track with our Headache Diary.
What happens next: a 12-week treatment schedule
Based on your progress, you and your doctor will discuss re-treatment every 12 weeks. Remember: BOTOX® is a preventive treatment, which means it's taken to prevent headaches and migraines from occurring. So, it is recommended that treatment be given once every 12 weeks.
The best way for you and your doctor to know if BOTOX® is meeting your treatment needs is to give it time to work, so talk to your doctor, and stay on track.
Ways to stay on track
Want to make sure you stay on schedule? Make your next appointment right after each treatment session—before you leave the office—so you don’t forget.
In addition, sign up for our Pathways to Prevention program, and we'll send you treatment reminders, along with fitness, diet, and healthy living tips from the editors of Prevention® Magazine.
Feeling your progress is one thing, seeing it on paper is another. As you begin to have fewer headache days, use our Headache Diary to track your progress, and see how far you’ve come!
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