Genome engineering refers to the strategies and techniques implemented for the modification of target genetic information of any living organism. Current advances in genome engineering is based on the programmable nucleases.

The global genome engineering market is anticipated to grow at a faster rate due to Increased funding in genomic research, technological developments, rising demand for synthetic genes, and investment by pharmaceutical companies for new product development. Advances in CRISPR-Cas9 genome engineering would positively impact future market growth. For instance, in November 2015, a new CRISPR technology was developed by scientists at the University of Massachusetts Medical School for cell analysis of large population and has most of the applications in gene therapy. The factors hampering the market growth are ethical issues like human germ-line modification, stringent regulatory framework and negative public perception related to genetic research.

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The global genome engineering market has been estimated based on technologies, application, end-user and geography. Based on technology, the global market has been segmented into Clustered Regularly-Interspaced Short Palindromic Repeats (CRISPR), Transcription Activator-Like Effector Nuclease (TALEN), Zinc Finger Nuclease (ZFN) and other technologies. CRISPR technology held the largest share of the market in 2014 and would continue to dominate the market during the forecast period.

The segment would also grow at highest CAGR during the forecast period. Based on application, the global genomic engineering market has been segmented into cell-line engineering, animal genome engineering, plant genome engineering and other applications. Cell-line engineering held the largest share of the market in 2014 and would continue to dominate the market during the forecast period. The segment would also grow at highest CAGR during the forecast period. Based on end-users, the global genomic engineering market has been segmented into Pharmaceutical and Biotechnology Companies, Academics and Clinical Research Organizations (CRO). The end-user segment, Pharmaceutical and Biotechnology Companies held the largest share of the market in 2014 and would continue to dominate the market during the forecast period. The Academics segment would also grow at highest CAGR during the forecast period.

Geographically, the genome engineering market has been categorized into four regions: North America, Europe, Asia Pacific, and Rest of the World (RoW). North America held the largest share of the genome engineering market in 2014, followed by Europe. North America covers major share due to high funding in genomic research and all the key players have their headquarters in the U.S. Asia Pacific was identified as the third largest market for genome engineering in 2014 and the region is expected to register fastest CAGR during the forecast period. Academic research spending would also propel the market in near future.

The key players in genome engineering market are Thermo Fisher Scientific, Inc., Sigma-Aldrich Corporation, Sangamo Biosciences, Inc., Lonza Group Ltd., Horizon Discovery Group Plc, Integrated DNA Technologies, Inc., are among the others. Thermo Fisher Scientific, Inc was identified as the leading player in the global Genome engineering market in 2014.

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