Increasing applications of bone graft substitutes in trauma, sports medicine, and spine surgery are high impact drivers of spinal fusion bone graft substitutes market. In addition, rising geriatric population base and changing lifestyles, and associated bone problems such as spinal degenerative diseases and osteochondral defects are the major drivers expected to propel the growth of this market. Introduction of technologically innovative products, increasing surgeon and patient awareness, and growing demand for minimally invasive procedures are the factors anticipated to boost the market growth.



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Demineralized Bone Matrix (DBM) is the segment having the largest market share in 2014 over the other segments such as bone morphogenetic proteins, synthetic bone graft extenders, stem cell therapy, and visco supplements. Benefits associated with this segment such as affordability, safety, and popularity among the patients are factors attributing to its large share. The bone morphogenetic proteins segment is expected to be the fastest growing owing to increasing demand for minimally invasive interventions and short procedure turnaround time. Stem cell therapy and visco supplements are expected to change the scenario in the global spinal fusion bone graft substitute market during the forecast period owing to higher efficacy and less morbidity. The market is also segmented by the materials used in the grafting; it includes natural, polymer, composites, and ceramics. Synthetic material segment is anticipated to witness a lucrative growth over the next seven years. Rising penetration of ceramics and composite has triggered the demand for synthetic material.



Geographically, North America is covering the largest share of the spinal fusion bone graft substitutes market and is expected to continue its dominance over the forecast period owing to the excellent healthcare infrastructure and growing R&D initiatives by the new companies. Asia pacific segment of the market is expected to show lucrative growth over the forecast period owing to increasing geriatric population, rising number of spinal bone graft surgeries, improving disposable income, and rising awareness regarding the use of these substitutes in the developing economies such as China and India.



Key players of this market include DePuy Synthes, Stryker, LifeNet Health, Integra LifeSciences, RTI Surgical, MTF, AlloSource, Biomet, Baxter, Bacterin International, Wright Medical, Biocomposites, Arthrex, Alphatec Spine, Berkeley Advanced Biomaterials, Osteogenics, and Etex Corporation. In 2013, Stryker, Synthes, and DePuy held the major share of spinal fusion bone graft substitutes market. Stryker focused on the bone graft substitute market with acquisition of Orthovita, the largest manufacturer of bone graft substitutes. Advancement in technologies and introduction of new substitutes are the factors expected to lead the growth of the market to a new level. For instance, the Smith & Nephew is mainly focusing on the development of innovative tissue repair solutions for sports medicine. TRUFIT BGS Plugs by Smith & Nephew, is indicated in the patients with osteochondral defects.


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