Global High Potency Active Pharmaceutical Ingredients Market is projected to reach USD 31.56 Billion by 2025, at a CAGR of 8.6% during the forecast period of 2018 to 2025.
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Market Segmentation: Global High potency active pharmaceutical ingredients Market
By Type
o Innovative HPAI
o Generic HPAI
By Type of Synthesis
o Synthetic HPAI
o Biotech HPAI
By Type of Manufacturer
o Captive HPAI manufacturer
o Merchant HPAI manufacturer
By Application
o Oncology
o Hormonal Imbalance
o Glaucoma
o Others
By Geography
o North America
o South America
o Europe
o Asia-Pacific
o Middle East and Africa

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Global High Potency Active Pharmaceutical Ingredients Market
High potency active pharmaceutical ingredients (HPAPI’s) the drugs which are highly effective in minute dosage than any generic API’s. HPAPI’s are classified on the basis of toxicity, pharmacological potency and occupational exposure limits. Generally HPAPI’s have very complex structure. Because of clinical pharmacology and research in oncology HPAPI’s have given more preference than API’s. When HPAPI’s combined with the antibody, the conjugate obtained have specific targeting nature that targets only the cancerous cells without affecting the non-cancerous cells. The HPAPI’s have more annual growth than API’s. For manufacturing of HPAPI’s new pharmaceutical plants are established with new technologies. HPAPI’s has occupational exposure limit (OEL) of ≤10μg/m3, daily therapeutic dose of ≤10mg/day or if a 1 mg/kg/day dose produces serious toxicity in laboratory animals. Few HPAPI’s developed by few companies are hydromorphone hydrochloride, vinblastine sulfate, vincristine sulfate, vindesine sulfate, vinorelbine tartrate,

FACTORS DRIVING GROWTH IN THE GLOBAL HIGH POTENCY ACTIVE PHARMACEUTICAL INGREDIENTS MARKET
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Increasing Insistence Of Oncology Drugs
Cancer is the one the disease which is growing with a great prevalence rate. As per of World Cancer Research Fund International, in 2012 around 14.1 million cases were observed all over the world. This number is expected to increase to 24 million by 2035. As per of new stats produced by the Cancer research U. K in 2017 total deaths happened were 1,66,135 among this 45% deaths were because of Cancers only. So by seeing this ratio to control the death from cancer new drug are required. HPAPI’s can play a major role in treating the cancer or other disease. Because of high action in minute amount the disease can be treated. HPAPI’s along with antibody had shown a significant action towards the cancerous cells without affecting the normal cells.
Increasing demand of Antibody-drug conjugate

When antibodies are joined with biologically active or chemical compound through chemical linkers. Antibody-drug conjugate have better action towards the cancerous cells than HPAPI’s because the HPAPI’s selectively targets the cancerous cells without affecting the normal healthy cells. Because of better mechanism of action of ADC than antibody or chemical drug, more research is going on for development of ADC’s which in turn enhances the HPAPI’s demand in the market.

Some of the major players operating in global high potency active pharmaceutical ingredients are
• Catalent, Inc,
• ANVI Pharma,
• Farmhispania Group,
• Quadro Engineering Corp,
• SAFC,
• Teva Pharmaceuticals industries Ltd ,
• Bristol Myers Squibb,
• Cambrex Ferro,
• Carbogen Amcis.,
• Mylan N.V.,
• AbbVie Inc,
• Eli Lilly and Company,
• Boehringer Ingelheim International GmbH,
• F. Hoffmann-La Roche,
• Lonza, Alkermes,
• Sanofi,

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