The global mice model (Models, services and care products) market is expected to grow at a CAGR of 7.2% during the projected period to reach USD 1,370.54 million by 2023 from USD 968.36 million in 2018. The growth of this market is mainly attributed to the continuing modification in mice model for cancers, immune diseases, and rare diseases; increasing devouring of personalized medicine propelling the demand for humanized mice model; rising grants and investments for biological research; rising pharmaceutical R&D activities; and increasing focus of International Mouse Phenotyping Consortium (IMPC) and International Knockout Mouse Consortium (IKMC) on the development of embryonic stem cells as well as knockout and mutant mice.

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The evolution of alternative techniques to animal testing, improvement in zebrafish model development, and growing need for improved mice models are the major challenges in the global mice model market. In addition, evolution of CRISPR-Cas9 gene editing technology in the field of biomedical research, increasing demand for humanized mice model, and rising monoclonal antibody production provides significant opportunities for the various stakeholders in the global mice model market. However, factors such as increasing use of rat models, increased advantages from cryopreservation, and government regulations and laws for ethical use of animals in research hampers the growth of mice model market to some extent.

MARKET DYNAMICS:

The continuous modification in mice model allows researchers to find out the appropriate solution for complex biology during the treatment of various chronic diseases. The mouse models are playing important role in the development of immune therapies. For instance, the recent research led by University of California developed a new class of drugs known as immune checkpoint inhibitors. These drugs have been used for the treatment of a growing number of patients with cancer, including some who had run out of treatment options.

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Cancer remains to be the second leading cause of death in the U.S., it was estimated that in 2017, 30% of all new cancer cases among women were breast cancer. In 2018, the federal budget prioritizes Medical Research and Cancer Prevention, which includes a $3 billion increase for medical research at the National Institutes of Health (NIH) a $275 million increase for the National Cancer Institute (NCI); a $10 million increase for cancer prevention programs at the Centers for Disease Control and Prevention (CDC).

TRENDS:

The rapidly growing ageing population and advances in cancer therapy have sparked tremendous interest in the improvement of mice models. For many years, cancer biologists have taken two distinct approaches to modeling cancer. One is to grow immortalized human cancer cells, known as cancer cell lines in a lab dish, but they don’t really reproduce the complex in vivo environment of a tumor.
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