Enzymes to help fight pathogens as they seem very safe and 'natural' and help as well as anything else. You can go up to many enzymes between meals if you want. Adding in a strong protease product (such as Purify or Peptide) with the yeast-killer (No-Felon, Candidate or other) between bio x4 meals would be something to consider. Proteases are thought to help breakdown the debris and carry it off so it is less likely to provoke die-off symptoms and discomfort. A general rule of thumb is to add 2 capsules of ....

http://www.supplementadvise.com/bio-x4/