Global In-vitro Toxicology Testing Market is estimated to value over USD 9.8 billion by 2026 end and is expected to register a CAGR of over 11% during the forecast period 2019 to 2026.
Biotechnological advancements in the field of toxicology have provided rapid, reliable and reproducible assays which have increased the demand for in-vitro toxicology testing. Additionally, these assays are capable of evaluating safety assessments and developmental problems which is assisting the pharmaceutical industry with timeless and cost-saving advantages for conducting toxicology tests for their candidate drugs, thereby boosting the market growth.
Furthermore, the experimental setup required for the in-vitro procedure is easy to operate compared to the in-vivo procedure and thus can prove efficient concerning the number of samples and time. There has been a paradigm shift from in-vivo to in-vitro method owing to societal concerns, animal welfare and extensive research which has assisted in the augmentation of the market.
Rising concerns regarding the search for alternatives to conventional animal testing is likely to proliferate the market. Animal welfare agencies are considering the possibility of completely replacing conventional animal testing methods with in-vitro toxicology testing. Additionally, they have introduced certain policies to reduce the dependency on animal testing and these factors shall augment the market growth.
Moreover, these assays are compliant with good laboratory practice (GLP) and thus can serve various life science domains such as pharmaceutical, biotech, cosmetic, chemical industries and consumer products. Such ubiquitous use of assays has projected to positively impact revenue generation in the market.
However, many pharmaceutical and cosmetic manufacturers still believe in using conventional animal testing as they provide better insights which can impede the market growth significantly.
But an introduction of a 3D cell culture system that imitates the host environment is projected to limit the usage of animal testing significantly thereby creating profitable opportunities for the market.
Cellular Assay Method Projected to Witness Significant Market Growth
A widespread presence of product portfolios of cellular techniques for studying drug products is the primary reason for cellular assay method to account for the largest market share. Additionally, a significant number of biotech companies are massively dependant on cell-based assays to conduct their research which is propelling the segment growth significantly.
Systemic toxicology is anticipated to dominate the market owing to its capability of generating precise data like information on minimum dosage resulting into toxicity, plasma concentration and maximally tolerated dose. These factors result in a margin of safety and toxicity which is used for decision-making purposes thus assisting segment growth.
The pharmaceutical industry led the market in 2016 due to the presence of several drug candidates in clinical phase which has resulted into a high usage of toxicology tests to understand the potential impacts of a particular drug on patients and for studying pharmacokinetics.
North America dominated the market in 2016 owing to governmental policies and favourable changes in regulatory guidelines for in-vitro toxicology assays which is why it is anticipated to continue its market dominance throughout the forecast period. Additionally, there has been a rise in the funds required for research activities which shall further augment the market growth of the region.
Some of the key market players include Agilent Technologies Inc., Abbott Laboratories (Alere Inc.), Bio-Rad Laboratories Inc., Merck KGaA, Charles River Laboratories International Inc., Thermo Fisher Scientific Inc., Catalent Inc., Eurofins Scientific, GE Healthcare, Quest Diagnostics Inc., LabCorp and EVOTEC.
FutureWise Key Takeaways:
• Animal welfare agencies are considering to completely replace conventional animal testing to in-vitro toxicology testing method and this paradigm shift will surely augment the market significantly
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Global In-vitro Toxicology Testing Market Segmentation:
By Technology
• Cell Culture Technology
• High Throughput Technology
• Molecular Imaging
• OMICS Technology

By Method
• Cellular Assays
• Biochemical Assays
• In-silico
• Ex-vivo

By Application
• Systemic Toxicology
• Dermal Toxicity
• Endocrine Disruption
• Occular Toxicity

By End-Use
• Pharmaceutical Industry
• Cosmetic & Household Products
• Diagnostics
• Chemical Industry
• Food Industry

By Region
• North America
• Europe
• Asia Pacific
• Latin America
• Middle East & Africa
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Competitive Landscape:
• Tier 1 players- established companies in the market with a major market share
• Tier 2 players
• Emerging players which are growing rapidly
• New Entrants

Objectives of the Study:
• To provide with an exhaustive analysis on the in-vitro toxicology testing market by technology, by method, by application, by end use and by region
• To cater comprehensive information on factors impacting market growth (drivers, restraints, opportunities, and industry-specific restraints)
• To evaluate and forecast micro-markets and the overall market
• To predict the market size, in key regions (along with countries)— North America, Asia Pacific, Europe, Latin America and Middle East & Africa
• To record evaluate and competitive landscape mapping- product launches, technological advancements, mergers and expansions
• Profiling of companies to evaluate their market shares, strategies, financials and core competencies
Table of Contents
Chapter 1 Executive Summary
1.1 Market Snapshot

Chapter 2 Research Methodology
2.1 Information Procurement
2.1.1 Purchased database
2.1.2 FutureWise’s Internal database
2.2 Data Analysis
2.3 Market Formulation & Validation
2.4 Approaches for Market Estimation
2.4.1 Approach 1: Commodity flow & bottom up approach
2.4.2 Approach 2: Top down and parent market analysis

Chapter 3 In-vitro Toxicology Testing Market: Variables, Trends & Scope
3.1 Market Segmentation & Scope
3.1.1 Market driver analysis
3.1.1.1 Rising need of food safety management as a consequence of growing food-borne illness
3.1.1.2 Successful implementation of high-throughput screening assays for toxicology testing
3.1.1.3 Alternative usage of in-vitro toxicology over animal testing
3.1.1.4 Technological innovations pertaining to toxicology testing
3.1.2 Market restraint analysis
3.1.2.1 Difficulty in implementation of in-vitro systems similar to in-vivo environment
3.2 Penetration & Growth Prospect Mapping For Methods,
3.3 In-vitro Toxicology Testing - SWOT Analysis, By Factor (political & legal, economic and technological)
3.4 Industry Analysis - Porter’s

Chapter 4 In-vitro Toxicology Testing Market: Technology Estimates & Trend Analysis
4.1 In-Vitro Toxicology Testing Market: Technology Movement Analysis
4.2 Cell-culture Technology
4.2.1 Global cell-culture technology market, (USD Billion)
4.3 High throughput Technology
4.3.1 Global high throughput technology market, (USD Billion)
4.4 Molecular Imaging
4.4.1 Global molecular imaging market, (USD Billion)
4.5 OMICS Technology
4.5.1 Global OMICS technology market, (USD Billion)

Chapter 5 In-vitro Toxicology Testing Market: Method Estimates & Trend Analysis
5.1 In-Vitro Toxicology Testing Market: Method Movement Analysis
5.2 Cellular Assays
5.2.1 Global cellular assays market, (USD Billion)
5.3 Biochemical Assays
5.3.1 Global biochemical assays market, (USD Billion)
5.4 In-silico
5.4.1 Global in-silico methods market, (USD Billion)
5.5 Ex-vivo
5.5.1 Global ex-vivo methods market, (USD Billion)

Chapter 6 In-vitro Toxicology Testing Market: Application Estimates & Trend Analysis
6.1 In-vitro Toxicology Testing Market: Application Movement Analysis
6.2 Systemic Toxicology
6.2.1 Global systemic toxicology market, (USD Billion)
6.3 Dermal Toxicity
6.3.1 Global dermal toxicity market, (USD Billion)
6.4 Endocrine Disruption
6.4.1 Global endocrine disruption market, (USD Billion)
6.5 Occular Toxicity
6.5.1 Global ocular toxicity market, (USD Billion)

Chapter 7 In-vitro Toxicology Testing Market: End-use Estimates & Trend Analysis
7.1 In-vitro Toxicology Testing Market: End-use Movement Analysis
7.2 Pharmaceutical Industry
7.2.1 Global pharmaceutical industry market, (USD Billion)

7.3 Cosmetics & Household Products
7.3.1 Global cosmetics & household products market, 2014 - 2025 (USD Billion)

7.4 Diagnostics
7.41. Global diagnostics market, (USD Billion)

7.5 Chemical Industry
7.5.1 Global chemical industry market, (USD Billion)

7.6 Food Industry
7.6.1 Global food industry market, (USD Billion)

Chapter 8 In-vitro Toxicology Testing Market: Regional Estimates & Trend Analysis, by Technology, Method, Application, & End-use
8.1 In-vitro Toxicology Testing Market Share By Region,
8.2 North America
8.2.1 North America in-vitro toxicology testing market, (USD Billion)
8.2.2 U.S.
8.2.2.1 U.S. in-vitro toxicology testing market, by technology, (USD Billion)
8.2.2.2 U.S. in-vitro toxicology testing market, by method, (USD Billion)
8.2.2.3 U.S. in-vitro toxicology testing market, by application, (USD Billion)
8.2.2.4 U.S. in-vitro toxicology testing market, by end-use, (USD Billion)
8.2.3 Canada
8.2.3.1 Canada in-vitro toxicology testing market, by technology, (USD Billion)
8.2.3.2 Canada in-vitro toxicology testing market, by method, (USD Billion)
8.2.3.3 Canada in-vitro toxicology testing market, by application, (USD Billion)
8.2.3.4 Canada in-vitro toxicology testing market, by end-use, (USD Billion)
8.3 Europe
8.3.1 Europe in-vitro toxicology testing market, (USD Billion)
8.3.2 Germany
8.3.2.1 Germany in-vitro toxicology testing market, by technology, 2014 - 2025 (USD Billion)
8.3.2.2 Germany in-vitro toxicology testing market, by method, (USD Billion)
8.3.2.3 Germany in-vitro toxicology testing market, by application, (USD Billion)
8.3.2.4 Germany in-vitro toxicology testing market, by end-use, (USD Billion)
8.3.3 U.K.
8.3.3.1 U.K. in-vitro toxicology testing market, by technology, USD Billion)
8.3.3.2 U.K. in-vitro toxicology testing market, by method, (USD Billion)
8.3.3.3 U.K. in-vitro toxicology testing market, by application, (USD Billion)
8.3.3.4 U.K. in-vitro toxicology testing market, by end-use, (USD Billion)
8.4 Asia Pacific
8.4.1 Asia Pacific in-vitro toxicology testing market, (USD Billion)
8.4.2 Japan
8.4.2.1 Japan in-vitro toxicology testing market, by technology, (USD Billion)
8.4.2.2 Japan in-vitro toxicology testing market, by method, (USD Billion)
8.4.2.3 Japan in-vitro toxicology testing market, by application, (USD Billion)
8.4.2.4 Japan in-vitro toxicology testing market, by end-use, (USD Billion)
8.4.3 China
8.4.3.1 China in-vitro toxicology testing market, by technology, 5 (USD Billion)
8.4.3.2 China in-vitro toxicology testing market, by method, (USD Billion)
8.4.3.3 China in-vitro toxicology testing market, by application, (USD Billion)
8.4.3.4 China in-vitro toxicology testing market, by end-use, (USD Billion)
8.5 Latin America
8.5.1 Latin America in-vitro toxicology testing market, (USD Billion)
8.5.2 Brazil
8.5.2.1 Brazil in-vitro toxicology testing market, by technology (USD Billion)
8.5.2.2 Brazil in-vitro toxicology testing market, by method, (USD Billion)
8.5.2.3 Brazil in-vitro toxicology testing market, by application (USD Billion)
8.5.2.4 Brazil in-vitro toxicology testing market, by end-use, (USD Billion)
8.6 MEA
8.6.1 MEA in-vitro toxicology testing market, (USD Billion)
8.6.2 South Africa
8.6.2.1 South Africa in-vitro toxicology testing market, by technology, (USD Billion)
8.6.2.2 South Africa in-vitro toxicology testing market, by method, (USD Billion)
8.6.2.3 South Africa in-vitro toxicology testing market, by application, (USD Billion)
8.6.2.4 South Africa in-vitro toxicology testing market, by end-use, (USD Billion)

Chapter 9 Competitive Landscape
9.1 Strategy framework
9.2 Market participation categorization
9.3 Company Profiles
9.3.1 Agilent Technologies Inc.
9.3.1.1 Company Overview
9.3.1.2 Financial Performance
9.3.1.3 Product Benchmarking
9.3.1.4 Strategic Initiatives
9.3.2 Abbott
9.3.2.1 Company Overview
9.3.2.1.1 Alere Inc.
9.3.2.2 Financial Performance
9.3.2.2.1 Financial Performance
9.3.2.2.2 Product Benchmarking
9.3.2.2.3 Strategic Initiatives
9.3.3 Bio-Rad Laboratories, Inc.
9.3.3.1 Company overview
9.3.3.2 Financial Performance
9.3.3.3 Product Benchmarking
9.3.3.4 Strategic Initiatives
9.3.4 Merck KGaA
9.3.4.1 Company Overview
9.3.4.1.1 Bio Reliance
9.3.4.1.2 Sigma Aldrich Corporation LLC
9.3.4.2 Financial Performance
9.3.4.2.1 Financial Performance
9.3.4.2.2 Financial performance
9.3.4.3 Product Benchmarking
9.3.4.4 Strategic Initiatives
9.3.5 Charles River Laboratories International, Inc.
9.3.5.1 Company Overview
9.3.5.2 Financial Performance
9.3.5.3 Product Benchmarking
9.3.5.4 Strategic Initiatives
9.3.6 Thermo Fisher Scientific Inc.
9.3.6.1 Company Overview
9.3.6.2 Financial Performance
9.3.6.3 Product Benchmarking
9.3.6.4 Strategic Initiatives
9.3.7 Catalent, Inc.
9.3.7.1 Company Overview
9.3.7.2 Financial Performance
9.3.7.3 Product Benchmarking
9.3.7.4 Strategic Initiatives
9.3.8 Eurofins Scientific.
9.3.8.1 Company Overview
9.3.8.2 Financial Performance
9.3.8.3 Product Benchmarking
9.3.8.4 Strategic Initiatives
9.3.9 GE Healthcare.
9.3.9.1 Company Overview
9.3.9.2 Financial Performance
9.3.9.3 Product Benchmarking
9.3.9.4 Strategic Initiatives
9.3.10 Quest Diagnostics Incorporated
9.3.10.1 Company Overview
9.3.10.2 Financial Performance
9.3.10.3 Product Benchmarking
9.3.10.4 Strategic Initiatives
9.3.11 LabCorp®
9.3.11.1 Company Overview
9.3.11.2 Covance Inc.,
9.3.11.3 Financial Performance
9.3.11.4 Product Benchmarking
9.3.11.5 Strategic Initiatives
9.3.12 EVOTEC
9.3.12.1 Company Overview
9.3.12.2 Cyprotex
9.3.12.3 Financial Performance
9.3.12.4 Product Benchmarking
9.3.12.5 Strategic Initiatives
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