Diflucan renders to the medical preparations for the fungous sicknesses’ medical cure. The main substance of preparation is Fluconazole. The matter possesses by the quality efficiently to suppress the sterols’ synthesis in the fungi’ cells. The medicine’s effectiveness is proved against the yeast and yeast-like fungi (Candida spp, Cryptococcus neoformans), musty fungi (Histoplasma capsulatum, Blastomyces dermatitides), dermatophytes (Trichophyton spp, Microsporum spp) and dimorphous forms (Coccidioides immitis). Diflucan is absorbed enough quickly from the digestive system reaching the maximum concentration after 0,5 – 1,5 hours after food applying. The food intake doesn’t influence on the remedy’s absorption. The period of partial ejection makes up about 26-30 hours that’s why the patients can use the drug one time per day. The widely distributed dosage is Diflucan 50mg 90 pills. Fluconazole penetrate to the tissues and liquids of man’s organism quite well. Its concentration in spinal fluid, saliva, bronchial secretion practically as in blood plasma but in the corneous skin layer the preparation accumulates in dosages exceeding the concentration in blood. The medicament doesn’t form the active metabolites and is gone away by the kidneys in practically uncontaminated view.
Diflucan drug’s applying
Diflucan is applied under the following diseases:
– the most distributed variant is genital candidiasis including sharp or recurrent vaginal candidiasis, prevention with goal of lessening relapses’ frequency of vaginal candidiasis (three and more episodes a year), candidal balanitis;
– candidiasis of mucous membranes including mucous oral cavity and pharynx, esophagus, noninvasive bronchial-pulmonary infections, skin-mucous and chronic atrophic candidosis of oral cavity, prevention of the candidosis’s relapse by the patients with acquired immunodeficiency syndrome;
-cryptococcosis including cryptococcal meningitis and infections of other allocation (for example, lungs, skin);
– generalized candidiasis including candidemia, disseminated candidosis and other forms of invasive candidal infection such as contagions of peritoneum, endocardium, eyes, respiratory and urinary tracts including the sick persons with malignant tumors, which are in the department of intensive care and receive the cytotoxic or immunosuppressive remedies;
– prevention of fungous infections;
– dermatomycosis (skin) including mycosis of foots, body, inguinal area, branny lichen, onychomycosis and skin candidal infections.
Realizing forms and dosages Diflucan
The effective daily dosage is calculated individually in depend of pathology and disease’s severity. For the genital candidosis as rule is needed one-time using of medicine. Diflucan’s applying under the other pathologies has to last for the disappearance of objective and subjective symptomatology. The patients with low immune status (AIDS, immunosuppressive therapy, malignant neoplasms) are in need in supporting medical cure after main therapeutic course’s completion. The widespread dosage is 400 mg per day. Under the heavy damages the daily norm makes up 200 mg/day. Patients may purchase this preparation in any twenty-four hours working online pharmacy.
Nonoperating effects Diflucan pills
In the most occurrences the treatment with remedy passes without nonoperating effects. In some causes it is observed some unfavorable effects such as
– from the nervous system’s side (headache, convulsions, dizziness);
– from the side of skin (allergic manifestations till Stevens-Johnson syndrome and Lyell’s syndrome, alopecia);
– from the gastrointestinal tract’s side (stomachaches, changes in the level of liver function tests, dyspepsia, toxic (medicinal) hepatitis, liver inadequacy);
– general (anaphylactic reaction, taste alteration, oppression of hemopoiesis).
Danocrine
Danocrine refers to the medical agents (androgens) which are mainly similar to the substance testosterone. This preparation oppresses some apportionment of the hypophysial gonadotrophic hormones (the hormones of hypophysis stimulated the formations of hormones in genital glands): luteinizing hormone (which calls the formation of ovary’s yellow body) and follicle-stimulating hormone (which stimulates the process of ovum ripening).In big dosages this medication renders the moderate androgenic (similar like action of male genital hormones) and anabolic (reinforced the protein synthesis) action. The widespread bought dose is Danocrine 100mg 90pills. Thanks to its action this remedy is often taken for treating of endometriosis (including with accompanying barrenness, benign new formations of lactiferous gland, fibrocystic mastitis and others), premenstrual syndrome, gynecomastia (increasing of mammary gland by men) and some other illnesses when it is necessary the suppression of gonadotrophic hormones’ secretion. This medicament is contra indicated for pregnant women, some female individuals who have a period of lactation, diabetes mellitus, cardiovascular sicknesses, kidneys and liver insufficiency and many others. This drug is also contra indicated together with powerful antidepressants, anti-anxious preparations, anticoagulants and anti-convulsive remedies. It is possible the strengthening of effect.
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