The global market for neglected tropical diseases should reach $2.6 billion by 2021 from $1.4 billion in 2016 at a compound annual growth rate (CAGR) of 14.1%, from 2016 to 2021.

Report Includes
-An overview of the global markets for tropical disease treatments.
-Analyses of global market trends, with data from 2015, estimates for 2016, and projections of compound annual growth rates (CAGRs) through 2021.
-A look at the total addressable market, an indication of the number of people affected, and the current shares of key marketed therapies.
-Representations of market shares by geography, company, and future outlook.
-Insight on some of the newer drug candidates, clinical trials, and their end points.
-Analyses of factors such as increases in resistance of vectors to common insecticides, increases in rapid diagnostic techniques, and no established treatment for newer conditions like Zika.
-Profiles of major players in the industry.

Study Goals and Objectives
The report provides an overview of neglected tropical diseases and explores evolving treatment options and market opportunities. Market deterrents, unmet needs and other factors that drive research are also discussed, while patents that highlight research priorities and predict future trends are analyzed.

The report examines regions as defined by the World Health Organization (WHO) and details estimated market size as well as forecasts through 2021 by region and disease. It also describes the contributions, investments and portfolios of some of the key players in this domain.

Reasons for Doing this Study
Pharmaceutical companies and research institutions prioritize research based on the needs of the market. Research and development is based on the return on investment dictated by market demand and consumer purchasing power. While the burden of tropical diseases and their unmet needs are huge, investment has been limited because the conditions affect communities that cannot afford exorbitant healthcare expenses.

However, with initiatives from organizations like the WHO, the Gates Foundation and collaborative research platforms like the Drugs for Neglected Diseases Initiative (DNDi), pharmaceutical and biotechnology players are now working together to support drug discovery and development. Due to the increased mobility of travelers and cargo, tropical diseases are no longer restricted to endemic regions and have now emerged in new areas, further highlighting the need for companies to focus their efforts on these debilitating and often deadly conditions.

The morbidity associated with recent outbreaks of Ebola and Zika have highlighted the unpreparedness of both the industry and government in dealing with viruses that were once endemic to regions such as Africa. The need for drug development for these indications is greater than ever and this study provides an overview of the collaborations, upcoming product launches and other factors driving the market.

Some of the currently marketed “Gold standard treatments” have started to prove ineffective due to the emergence of parasite resistance, necessitating the need for the discovery of drugs with different mechanisms of action. This report includes market intelligence on some of the newer candidates in the drug development pipeline, listed by disease, as well as patents being filed.

Scope of Report
The report focuses on newer drugs and innovations in chemical compounds, vaccines and biologicals recently launched or in development. Specifically excluded from the scope of research are vector or mosquito control approaches, strategies and products; drugs used for symptomatic treatment and not for the elimination of the virus from the host; and details on manufacturers and suppliers of nonbranded generics.

Products used for diagnosis as well as PCR techniques, kits and testing facilities are also excluded from the report.

Research has categorized the markets based on regions defined by the WHO since it is the primary organization mapping disease prevalence, assisting with access to medicine and enabling partnerships. Regions include Africa, Americas, South-East Asia, Europe, Eastern Mediterranean and Western Pacific. These cover all the WHO participating countries which are described in detail in the subsequent section.

Information Sources
Research conducted a comprehensive literature search that included technical newsletters, published patent applications, company public releases, whitepapers and journals, and several other sources. Data were collected through interviews and correspondence with key opinion leaders in the industry.

Methodology
Both primary and secondary research methodologies were used in preparing this study. Projections were based on estimates such as disease incidence, coverage of vaccine programs and the WHO’s access to medicine programs.

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