"Cardiovascular Disorders Drug Development Pipeline Review, 2017-Market Research Report Store＂published in April 2017. It is a professional and in-depth study.

Summary:
Market Research Report Store announces a new report＂Cardiovascular Disorders Drug Development＂added to its database.Cardiovascular disease (CVD) covers a range of difference diseases and conditions affecting the heart and/or blood vessels. The most crucial risk factors for CVD are hypertension and dyslipidemia of which accelerate the development of atherosclerotic plaques building up within blood vessels. As atheroma develops its causes stenosis of the blood vessels which can restrict blood flow to the body, brain or heart depending on its locale. It is also possible for the fibrous cap of the plaque to break off, triggering the coagulation cascade and causing a thrombus to form locally which can completely occlude blood flow.

The treatments of CVD typically focus on prevention by controlling the risk factors of CVD. As such, the treatments usually fall within three categories: Anti-hypertensives aim to lower blood pressure; anti-dyslipidemia drugs aim to alter lipid levels to an acceptable range; and anti-thrombotic drugs aim to either prevent thrombus forming or work to mitigate the damage of a current thrombi, they do this by either interrupting the coagulation cascade or inhibiting platelet aggregation, both of which inhibit blood from clotting.

There are over 1,200 pipeline products within the CVD therapy area. Over 50% of these products are small molecules however there is also diversification with regards to molecule types within the pipeline. In addition, the molecular targets in the pipeline are considerably diverse with a high frequency of products acting on targets related to lipid metabolism and those which act on elements of the coagulation cascade.

Among those pipeline drugs expected for imminent release to market there is a mixture of first-in-class products, typically anti-dyslipidemia drugs aiming to provide alternatives to statin therapy, and drugs belonging to currently popular classes such as PCSK9 inhibitors and direct factor Xa inhibitors.

Complete Report Available at: @
https://www.marketresearchreportstore.com/shop/cardiovascular-disorders-drug-development-pipeline-review-2017

Scope

– Which companies are the most active within the pipeline for CVD?
– Which pharmaceutical approaches are the most prominent at each stage of the pipeline and within each indication?
– To what extent do universities and institutions play a role within this pipeline, compared to pharmaceutical companies?
– What are the most important R&D milestones and data publications to have happened in this disease area?

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Some points from Table of Contents

GBI Research Report Guidance 2
Executive Summary 3
Table of Contents 4
List of Tables 6
List of Figures 15
Introduction 18
Cardiovascular Disorders Report Coverage 18
Hypertension Overview 18
Dyslipidemia Overview 18
Thromboembolism Overview 18
Heart Failure Overview 18
Therapeutics Development 20
Hypertension 20
Dyslipidemia 22
Thromboembolism 24
Heart Failure 26
Therapeutics under Development by Companies 31
Hypertension 31
Dyslipidemia 35
Thromboembolism 39
Heart Failure 40
Therapeutics under Investigation by Universities/Institutes 47
Hypertension 47
Dyslipidemia 49
Thromboembolism 50
Heart Failure 50
Pipeline Products Glance 52
Hypertension 52
Dyslipidemia 55
Thromboembolism 58
Heart Failure 61
Products under Development by Companies 68
Hypertension 68
Dyslipidemia 75
Thromboembolism 79
Heart Failure 79
Products under Investigation by Universities/Institutes 86
Hypertension 86
Dyslipidemia 87
Thromboembolism 88
Heart Failure 88
Companies Involved in Therapeutics Development 90


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