Kary Mullis in the 1980s developed a revolutionary technique that is now the basis of the global polymerase chain reaction (PCR) market. The basic concept of PCR is to use a DNA polymerase to synthesize completely new strands of DNA. These strands will be similar to the template DNA strand used. One of the core requirements in the process is the addition of a primer. This is required because a DNA polymerase can only add a nucleotide to a 3’-OH group that already exists. The primer helps the polymerase to add the first nucleotide. Using this method, a scientist can create billions of copies of any specific sequence he/she wants. The core components of PCR are therefore a DNA template, a DNA polymerase, and nucleotides.

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The techniques used in the global PCR market have created a giant scope of innovation in the world of science in terms of DNA-based research molecular diagnostics. PCR allows for the absolute quantification of DNA and RNA, both of which are genetic materials.

Commercial Labs Boost the Global PCR Market

Till recent times, the global PCR market has found scope mostly in pharma and biotechnology industries apart from research institutions. The rise of commercial diagnostic laboratories is set to change this confined trend. A large number of labs, both private commercial and government, are beginning to prefer PCR for the accurate diagnosis of life-threatening diseases including cancer and Ebola. Large players in the diagnostics industry are now building standalone labs with minimal infrastructure to provide PCR.

Player Trends and Innovations that Drive the Global PCR Market

All the top companies that operate in the global PCR market are currently working on developments that enhance the functionalities in it. This includes creating a broader list of tests and a higher level of specificity and sensitivity. Some of the key innovations that have defined the global PCR market today are the significant reduction in turnaround time, the ability to create automated workflow, and higher productivity. All developments in the global PCR market focus on the fact that there needs to be an extremely high level of accuracy in the detection and amplification of genetic materials.

There is a major shift in technologies happening in the global PCR market. This involves the increasing preference of real time and/or digital PCR systems. The market’s innovations will create a stronger foundation for future activities. For example, the introduction of QX200 Droplet Digital PCR system by Bio-Rad offers a plethora of tests for molecular diagnostics. Their improved workflow will reduce overall costs in the global PCR market.


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Reagents and Consumables Dominate the Global PCR Market

The largest products segment in the 2013 global PCR market was reagents and consumables, when it generated a total of US$4,072.2 million for multiple companies. As for the applications segment, more than 48% of the 2013 global PCR market was held by life sciences. Clinical diagnostics held more than 33% of the market share in the same category. Life sciences dominates this category due to a greater level of acceptance of PCR oriented methods in cancer research, which happens to be one of the oldest application segments in the global PCR market. Academics and research has remained the largest end user of the global PCR market for the longest time and continued its dominance till 2013.

The global polymerase chain reaction market had a past worth of US$6.1 billion at the end of 2013. Market analysts now say that this market is currently developing at a compound annual growth rate of 6.6% between 2014 and 2020. If this growth rate remains unchanged, the global polymerase chain reaction market could potentially be worth US$9.6 billion by 2020. With its wide application base and growing number of commercial labs, the market is set to show a good deal of promise to all the players in it.

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