Microneedle flu vaccine is still in nascent stage of development however, after its launch it would provide various advantages over conventional needle-based vaccines, which will drive growth of the market. Microneedle vaccine can be delivered easily at any location without special storage infrastructure, therefore it can be used even at distant location. This vaccine can be self-administered by anybody thereby, eliminating the need of clinic visit and assistance of physician. This serves as an important advantage, especially in the emerging markets, where there is severe shortage of healthcare workers.

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According to World Health Organization, 2017 factsheet, Africa had an average of 1.30 health workers per 1000 population in 2015, which is way below the 4.5 per 1000 required for achievement of Sustainable Development Goals (SDGs). Globally, health workforce shortage is estimated to be 14.5 million, out of which Africa has the most severe health workforce (HWF) shortage, estimated to reach 6.1 million by 2030. Microneedle vaccine can address these issues if utilized on global scale. Moreover, it would avoid deaths caused from unavailability of vaccine by improving access to vaccination. For instance, according to United Nations Development Programme, measles vaccines have averted nearly 15.6 million deaths since 2000, globally.

Microneedle vaccines are safe and without any serious life threatening or adverse effects. These vaccines do not create sharp waste, thereby eliminating the problem of discarding needles. Patients suffering with needle phobia can easily use microneedle flu vaccine. According to a study published in Behavioral Neurology, 2014, around 3-4% of the world population faces needle phobia. This impacts their hospital or clinic visits, as they avoid visiting such facilities due to fear of exposure to needles.

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Needle phobia also impacts the vaccination amongst children, as most of them perceives injecting vaccine as a painful procedure. According to a study published in the Clinical Journal of Pain in 2015, there were 12 billion vaccination every year worldwide, most of which required injecting drug with a needle syringe system. Microneedle vaccine could reduce overall cost of vaccination.

In June 2017, National Institutes of Health-funded study led by a team at the Georgia Institute of Technology and Emory University published a report in the journal Lancet, which shows that an influenza vaccine can produce robust immune responses and be administered safely with an experimental patch of dissolving microneedle. Participants in the study preferred microneedle flu vaccine over other types of vaccines.

There is increased amount of research funding to develop commercially available micro needle flu vaccine, which would pace up the launch of these products. In 2015, the Georgia Institute of Technology and Micron Biomedical were awarded US$ 2.5 million in grants from the Bill & Melinda Gates Foundation to advance the development of dissolvable microneedle patches for polio immunization. This would also widen up the disease profile for which microneedle vaccine could be developed.

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Key players in the global microneedle flu vaccine market are Micron Biomedical, Microdermics Inc., 3M Company, Inc., VaxInnate, and Vetter among others.

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