Single-use bioprocessing system is majorly used in the upstream and downstream bioprocessing method. Moreover, key advantages offered by single-use bioprocessing such as cost reduction, increased productivity, low energy and water consumption during bioprocessing, easy disposable and reduced risk of cross contamination allows its easy and increased adoption over conventional bioprocessing systems. Moreover, government regulatory organizations are majorly adopting single-use bioprocessing systems, owing to its advantges. For instance, Australian Government: Therapeutic Goods Administration (TGA) allows the use of single-use systems in buffer preparation, mixing, and other upstream processing. Apart from this, TGA also proposed GMP regulation for filters, equipment used in single-use systems.
Furthermore, increasing demand of biopharmaceuticals, growing investment on research and development activities and increasing number of key players offering affordable and technologically advanced disposable bioprocessing products are projected to drive growth of the single-use bioprocessing systems market over the forecast period.
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Single-use bioprocessing system is a disposable bioprocessing process in which the systems such as disposable bioreactor, single-use bags, and disposable filters are disposed after use instead of cleaning or sterilization. Single-use systems are majorly adapted in upstream and downstream bioprocessing, owing to its benefits over conventional bioprocessing systems, which includes reduction of cost, increased speed of implementation, and reduced risk of cross-contamination. Moreover, increasing adoption of single-use bioprocessing systems, increasing investment in research and development (R&D) sector by various government and private organizations, increasing demand for single-use systems in biopharmaceutical sector and increasing number of key players offering technologically advanced bioprocessing products are projected to augment growth of the single-use bioprocessing systems market over the forecast period.
The global single-use bioprocessing systems market was valued at US$ 2.80 billion in 2018, and is expected to witness a CAGR of 17.2% over the forecast period (2018 – 2026).
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Increasing demand for biologics, need for production capacity expansion, patent expiry of blockbuster molecules, and a limited number of potential products in the pipeline have driven the companies to adopt new technologies such as single-use bioprocessing systems. Single-use equipment offers various benefits making biomanufacturing process more efficient and cost effective. Single-use technologies is a rapidly evolved and adopted owing to their ability to offer significant cost reduction, ease of disposable, time saving, less energy and water demand for bioprocessing process, reduced risk of contamination and increase in productivity. Moreover, single-use bioprocessing systems reduces the initial investments and research and development (R&D) cost involved in the manufacturing of biologics and biopharmaceuticals.
Conventional manufacturing of biopharmaceuticals and biologics involves use of stainless steel-based bioreactor and their subcomponents. Most of these products require sterilization and associated units for manufacturing contamination-free bio-products and biologics, which significantly increases overall investment cost. Moreover, according to the data published in Bioprocess International Journal in December 2015, single-use bioprocessing systems eliminate additional investment cost, as sterilization is not required. This lower around 40% of investment costs compared to stainless steel facility.
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