Skin and Soft Tissue Infections (SSTIs) are one of the reason for high rate of morbidity and mortality. Even, in the cases of successful surgeries, affected subcutaneous tissue, fascia, or muscle; remains a delay in the healing process and can lead to life-threatening conditions. This cases are propelling demand for more effective treatments to deal with such pathological situations. Recently, wound dressings loaded with antimicrobial agents has emerged as potential option to reduce wound bacterial colonization and infection to improve the healing process.
Antimicrobial wound dressing contains drugs such as antimicrobial agents, biologics such as growth factors, or they are composed of materials derived from animal sources. These dressings prevent bacterial penetration into the wound and avoid growth of microorganisms. The commonly encountered antiseptic agents in the antimicrobial dressings are silver, iodine, chlorhexidine, Polyhexamethylbiguanide (PHMB), alginate, and hydrocolloids.
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Conventional wound dressings take longer time for wound healing as compared to advanced wound dressing products such as antimicrobial and anti-infective wound dressings, which are widely used in post-operation to prevent risk of any Hospital Acquired Infections (HAIs). Antimicrobial wound dressings are rapidly replacing conventional wound dressings due to their high functional efficiency and effectiveness.

Increasing incidence of burns, trauma wounds and injuries, and diabetic ulcers are expected to drive growth of the global antimicrobial wound dressings market over the forecast period. For instance, in January 2017, according to the World Health Organization (WHO) data published in African Journal of Emergency Medicines, burn cases accounted for around 18 million disability cases and more than 2,50,000 deaths annually, out of which over 90% deaths were reported in low- and middle-income economies.
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The U.S. fire department responded to around 1.3 million fire incidences in 2016, out of which 3,280 civilian deaths and 15,700 civilian injuries were reported by National Fire Protection Association (NFPA).
Chronic wounds have a significant impact on the health and quality of life and their families, causing pain, emotional stress, restriction of daily activities and stress, depression, distress, and anxiety, with prolonged hospital stay, and chronic morbidity. For instance, according to the data published by Agency for Healthcare Research & Quality (AHRQ), in October 2014, over 2.5 million individuals in the U.S. develop pressure ulcers annually, which costs the U.S. health care system around US$ 9.1 billion to US$ 11.6 billion annually.
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