Calciphylaxis Treatment Market - Size, Share, Trends, and Forecast to 2026


Posted December 19, 2018 by sumitpatil

Calciphylaxis or Calcific Uremic Arteriolopathy (CUA) is the most severe form of cardiovascular calcification in dialysis patients.

 
Calciphylaxis or calcific uremic arteriolopathy is a syndrome of vascular calcification, thrombosis, and skin necrosis. It mostly occurs in patients with end-stage kidney disease or kidney transplant. Calciphylaxis results in chronic non-healing wounds and is usually fatal. It has a high mortality rate, owing to cardiovascular disease and sepsis caused due to infected skin ulcers. The exact pathogenetic mechanisms of the disease is not known. Most patients with the condition have abnormalities in blood-clotting factors. Multiple interventions are used to treat calciphylaxis, including restoring oxygen and blood flow to the skin, decreasing calcium deposits, and intensive wound treatment.
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Market Dynamics
High prevalence of kidney diseases and increasing number of clinical trials in the field of calciphylaxis treatment are major factors expected to drive growth of the calciphylaxis treatment market. According to the National Institute of Diabetes and Digestive and Kidney Diseases Health Information Center, in 2016, the overall prevalence of chronic kidney diseases in the U.S. was around 14% of total population.
Calciphylaxis has no approved treatment, which has led to increasing number of clinical trials and research, which is expected to fuel growth of the market. For instance, in March 2015, the Multidisciplinary Calciphylaxis Program launched the first randomized trial for treatment of calciphylaxis with research focus on the role of vitamin K in the treatment of the disease.

Increasing clinical trials in the field of calciphylaxis is expected to drive the calciphylaxis treatment market revenue
According to the Journal of General Internal Medicine 2014 study, calciphylaxis has an increasing incidence trend and a 50% mortality rate within the first year of onset. High prevalence of kidney disease is a major factor for incidences of calciphylaxis. According to the National Institute of Diabetes and Digestive and Kidney Diseases Health Information Center, in 2016, over 661,000 Americans had kidney failure and 468,000 of these patients were on dialysis.
Various academic research institutes and companies are focused on developing suitable treatment for calciphylaxis. For instance in March 2018, Sanifit successfully completed a Phase II trial of the first effective treatment for calciphylaxis. Moreover, in 2014, researchers at the National Kidney Foundation reported successful application of intravenous (IV) pamidronate to treat calciphylaxis in patients with End-Stage Renal Disease (ESRD).
Detailed Segmentation:
• Global Calciphylaxis Treatment Market, By Treatment:
◦ Drug Therapy
◦ Hyperbaric Oxygen Therapy
• Global Calciphylaxis Treatment Market, By End User:
◦ Hospital and Clinics
◦ Homecare
◦ Ambulatory Centers
Calciphylaxis Treatment Market - Regional Insights
On the basis of region, the global calciphylaxis treatment market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America calciphylaxis treatment market is expected to foresee major revenue share, owing to increasing government support and funding to treat calciphylaxis patients. According to the National Kidney Disease Education Program study 2015, in the U.S., treatment of chronic kidney disease surpasses US$ 48 billion, annually and the ESRD program consumes 6.7% of the total Medicare budget to care for less than 1% of the covered population.

Key Players:
3M,
Amgen Inc.,
BSN Medical,
ConvaTec Inc.,
Medtronic Plc.,
Smith & Nephew Plc.,
Laboratoris Sanifit S.L.
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Issued By Coherent Market Insights
Country India
Categories Health
Tags growth , market , shares , treands
Last Updated December 19, 2018