The Global Bone Grafts and Substitutes Market size valued USD 2.96 billion in 2019, and is predicted to reach USD 4.85 billion by 2030, witnessing a CAGR of 4.5% from 2020-2030.

Bone grafting is a surgical procedure to operate extremely complicated bone fractures whereas bone grafts are implantable materials, used during the procedure to promote bone healing, bone formation, and osseous reconstruction. Depending on the grafting procedure, the bone grafts may be autologous, allograft or synthetic with mechanical properties replicating the bone. These grafts soon get reabsorbed and replaced with the healing of natural bone, and their efficacy depend on three basic principles viz. osteoconduction, osteoinduction, and osteogenesis. Bone grafts hold wide applications in spinal fusion, trauma, dental bone grafting, craniomaxillofacial, joint reconstruction and other bone grafting procedures.

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Top Companies: Johnson & Johnson, Arthrex, Inc., Baxter International Inc., Zimmer Biomet Holdings, Integra LifeSciences Holdings Corporation, Wright Medical Group N.V., Stryker Corporation, Musculoskeletal Transplant Foundation, NuVasive, Inc., Medtronic Plc., Inc. and others.

The bone grafts and substitutes market share analysis is based on type, application, end user, and geography. Based on type, the market is segmented into bone graft substitutes, allograft, and cell-based matrices. Based on application, the market covers spinal fusion, trauma, dental bone grafting, craniomaxillofacial, and joint reconstruction. Based on the type of material, the bone grafts and substitutes market is divided into collagen, hydroxyapatite, tricalcium phosphate, human cell source, animal source, and others. Geographic breakdown and analysis of each of the previously mentioned segments include regions comprising North America, Europe, Asia-Pacific, and RoW.

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North America region is expected to dominate the global bone grafts and substitutes market throughout the forecast period, accounting for the highest market shares. This is attributed to factors such as well-established orthopedic specialty healthcare infrastructures, better reimbursement facility, higher adoption of advanced medical technologies, higher investments in R&D activities, and presence of key players in this region. It is expected that the emerging economies, specifically in the Asia-Pacific region shall witness increasing size of the bone grafts and substitutes market, owing to rapidly increasing geriatric population, growing adoption of bone grafts and substitutes in grafting modalities, as well as presence of large patient pool migrates in this region.

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