The Active Pharmaceutical Ingredients are an important part of the pharmaceutical industry. That’s because they are useful in drug preparation. Demand for APIs has grown significantly. The API market of India is the third largest in the Asia-Pacific region and is among the top five in the world. The Indian API manufacturers focus on expanding their business in regulated markets such as the US and Europe. Their effort to attain this goal is by increasing the production of important APIs, improvising on the methods of production, increasing capacity, and so on.

According to a new report published by RNCOS, named, “Indian API Market Outlook 2022”, the pharmaceutical industry in India is in an urgent need for new scientific advances that would yield innovative and effective drugs and therapies. This need is an important factor driving the growth of the API industry in the country, which has led to the invention of a new generation of APIs. One example of the new generation of APIs is ionic liquids. Ionic liquids with biological activity are used as APIs. There is a particular focus on efforts to overcome current hurdles encountered by APIs.

Ionic liquids are organic salts with melting points below 100°C and composed entirely of ions. These are known as ‘designer solvents’ because of their use as solvents at room temperature a property that has enabled the use of ionic liquids as a reaction media to produce or improve the preparation of various pharmaceuticals. Apart from this, ionic liquids can also be used as pharmaceutical solvents or co-solvents for the delivery of drugs with poor water solubility.

They are also applied in micro-emulsion systems, which can facilitate the dissolution of drugs that are insoluble or poorly soluble in water. Some ionic liquid micro-emulsions can be used as modern colloidal carriers for topical and transdermal delivery, while other ionic liquid systems have been used as entrapped/solubilized drug reservoirs for controlled release.

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