Aptamers market Overview
Aptamers are oligonucleotides that bind to target protein, lipid, or nucleic acid molecules with a more specificity. Aptamers are generated quickly and applied in the inhibition, characterization of proteins and for particular detection. Aptamers can be used as pharmaceutical leads, detection reagents, functional proteomic levels with antibodies, and small molecules. Aptamers can be engineered to have high specificity and affinity for number of targets.

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The enormous opportunities offered by the market for the main players are the drug discovery, biomarker discovery, and diagnostics segments. The launch of Macugen, the first aptamer drug and first diagnostic test for testing mycotoxins in grains has acknowledged the potential of aptamers in diagnostics and therapeutics. So, the global market for aptamers is expected to raise, backed by technological advancements with respect to selection processes and synthesis.

The main factor driving the growth of the market are technological advancements, increasing R&D investments in pharmaceutical and biotechnology industries, low cost and high efficiency in binding to large molecules compared to antibodies and the patent expiration of systematic evolution of ligands by exponential enrichment technology (SELEX) will boost the market positively. Stringent regulations in use of aptamers, Ethical issues of the aptamers that are acquired from the animals, slow in reaching the market place owing to regulatory hurdles are hindering the growth of this market.

Aptamers market Forecast Report (2018-2023)
Aptamers Market worth was $ 178.27 million in 2018 and estimated to reach $ 407.84 million by the end of 2023 with a growing potential of 16.5 %.

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Aptamers market Segmentation
Aptamers Market is broadly segmented based on type into Peptide aptamers, Nucleic Acid aptamers. Nucleic Acid aptamers are further segmented into DNA-Based Aptamers, RNA-Based Aptamers, and XNA-Based Aptamers. DNA Based Aptamers has the highest share in the market and XNA based Aptamers accounts to have high CAGR over the forecast period.
Based on Application the market is segmented into Therapeutics Development, Diagnostics, Research and Development and on the basis of end users the market is categorized into Pharmaceutical Companies, Bio-Pharmaceutical companies, Academic and Research Centres. North America dominates the global Aptamers market with main share followed by Europe, Asia - Pacific. Asia-Pacific is expected to account utmost growth during the forecast period.

Key Developments in the Market
• November 2017: The Base Pair Biotechnologies closed a USD 3.2 million Series A-3 financing round. Base Pair gives custom aptamer discovery and development services, as well as a line of catalog aptamers. The company said it would use the financing to acquire new lab instruments and other technology in order to enlarge its cellular and molecular analysis capabilities, as well as to expand its team.
• December 2017: The Caris Life Sciences identified new mechanism of action for an aptamer with therapeutic potential to treat non-Hodgkin lymphoma.

Major Players:
Some of the major companies dominating the current market are
• AM Biotechnologies
• Aptagen
• Aptamer Sciences Inc.
• Aptamer Solutions Ltd.
• Aptus Biotech S.L.
• Base Pair Biotechnologies Inc.
• Neo Ventures Biotechnology Inc.
• SomaLogic Inc
• Trilink BioTechnologies Inc.
• Vivonics, Inc.

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