Carbimazole(CBZ) is a thiourea based, thyrostatic or an antithyroid drug which is used for the treatment of hyperthyroidism. Hyperthyroidism is a condition that occurs due to excessive production of thyroid hormone by the thyroid gland. This condition leads to symptoms like irritability, muscle weakness, sleeping problems, a fast heartbeat, heat intolerance, diarrhea, enlargement of the thyroid, and weight loss.
Carbimazole is a prodrug of its active form Methimazole (Thiamazole), which works by preventing thyroid peroxidase enzyme from coupling and iodinating the tyrosine residues on thyroglobulin, and hence reduces the production of thyroxines.
Carbimazole is a prominent drug which is required to maintain thyroid hormones which are essential for the development and differentiation of all cells of the human body.
Methimazole (Thiamazole) which is an active metabolite of its prodrug Carbimazole is also known as Carbimazole impurity A.
In-house Reference standards of Carbimazole API and Carbimazole impurity A are available at Pharmaffiliates Analytics and Synthetics P. Ltd. in pack sizes of 25mg and 50mg and are more than 98% pure. Customized pack sizes are also available at Pharmaffiliates.
All the above mentioned reference material are readily available in stock at Pharmaffiliates and these are delivered in a time and cost- effective manner. Complete structure elucidation and data interpretation with high end analytical techniques like NMR, MASS and Chromatographic purity along with detailed Certificate of Analysis are also provided at Pharmaffiliates.