Fill-finish manufacturing is the process of aseptically filling biologics in any form such as solution, powder, or suspension in containers such as vials, syringes, cartridges, ampoules, bottles, and bags.

It is an integral part of biopharmaceutical manufacturing after upstream-cell culture & downstream-separation and purification operations. Key steps involved in the fill-finish process include cleaning, sterilization, filling, stoppering, lyophilization, capping, crimping, and visual inspection.

The fill-finish manufacturing market is expected to reach USD 4.47 Billion by 2022 from USD 2.96 Billion in 2017, at a CAGR of 8.6%. The base year considered for the study is 2016 and the forecast for the market size is provided for the period between 2017 and 2022.

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Target Audience:

# Biopharmaceutical companies
# Fill-finish product manufacturers
# Contract manufacturing companies
# Clinical research organizations
# NGOs and government organizations associated with fill-finish manufacturing
# Market research and consulting firms

The contract manufacturing organizations segment expected to grow at the highest rate in the next five years

On the basis of end user, the market is classified into contract manufacturing organizations, biopharmaceutical companies, and other end users. The contract manufacturing organizations segment is the fastest-growing segment in the fill-finish manufacturing market. This can primarily be attributed to the rising demand for outsourcing the fill-finish manufacturing process and growing number of new entrants in the biologics manufacturing market.

Geographically, the fill-finish manufacturing market is segmented into North America, Europe, Asia Pacific, and the Rest of the World (RoW). In 2017, Europe is expected to account for the largest share of the global market. The large share of the European region is mainly attributed to factors such as the emergence of biosimilar market due to patent expiry of key biologic products, rising incidence of chronic disorders, and the increasing focus of major players on increasing their presence in Europe. The APAC region is projected to grow at the highest CAGR during the forecast period. The growth of the global market in this region is driven by the overall growth in the biopharmaceutical industry.

Isolators and RABS are equipped with advanced features and functionalities and are therefore priced at a premium, as compared to standalone systems. This severely restricts their accessibility, especially for small companies. Owing to this, the adoption of isolators and RABS is very low as compared to standalone systems in underdeveloped or developing countries, including China and India. Furthermore, research institutes find it difficult to afford such instruments, as they have restricted budgets for the purchase of such instruments. The use of standalone systems still prevails among these end users.

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