As the growth of Covid-19 hit all over the world, medical experts are continuously working hard to overcome the situation. Testing is the only way to control the situation till no vaccination is found by the health experts worldwide to control the global pandemic.

Manufacturing of kits in massive quantity was suddenly raised because of the global pandemic and the urgent need for diagnostic and antibody tests triggered an unprecedented scramble among medical manufacturers. To meet the requirement, the manufacturers are developing reliable rapid diagnostic test kits that are relatively simple to perform and provide results as soon as possible. Many diagnostic tests are available so far with more gaining emergency approval every day.

The major tests to detect the Covid-19 virus are Antigen and Antibody test.

Antibodies are protective proteins produced naturally in response to seeing antigen (foreign structure) for e.g viral infection. The antigen is a structure recognized as a foreigner by the human body to trigger the immune system to produce self-defense systems to clear pathogens from blood and tissues. Antigen clearance is spearheaded by antibodies and white blood cells.

Rapid diagnostic test (RDT) detect the presence of viral protein (antigen) expressed by the covid-19 virus in a sample from the respiratory tract of a person. This test is best used to identify acute or early infection in the suspected body. The body produces early ‘prototype’ antibodies (IgM) with intermediate strength for the binding virus. This can clear the virus in 5 days after the infection started.

The antibodies act as developing a matching contoured surface to stick to antigen using a sophisticated selection process to amplify antibodies with the best surface match and strongest binding. The major benefit of testing is that it provides an indication of what phase of infection the patient may be in.

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