Aptamers Market is Projected to Witness Strong Growth Owing to Associated Advantages over Antibody based Assays


Posted April 13, 2019 by mayank12

According to the latest study published by AnalystView Market Insights, by the end of 2025

 
Global aptamers market is expected to reach USD 9,125.6 million, growing with an impressive growth rate of 30.2%. This proposed study provided comprehensive analysis on Aptamers market based on its growth potential, market drivers, barriers, future opportunities, strategies adopted by key players for surviving in market, and detailed qualitative analysis for industry segments. Strategic analyses such as Porter’s five forces, PEST analysis, leading companies’ market share (value %), pipeline study and value chain analysis will also be included which will help you to take strategic decision with respect to this market.

Aptamers are short single stranded oligonucleotide and peptides that enable to bind with the target molecule with high specificity and affinity. Aptamers are selected through in vitro procedure, based on affinity towards the target molecule, which can be a virus, protein, or cell. Systematic Evolution of Ligands by Exponential enrichment (SELEX) is primarily utilized iterative enrichment technique to identify quality aptamers. Factors such as increasing demand for cost effective therapeutics, rising research and development activities, increasing number of companies coupled with advantages over antibodies support the market growth to great extent. Furthermore, increasing number of aptamers under late stage clinical trials boost the market scope.
Currently, around ten aptamers are under distinct phases of clinical studies for the treatment of neo-vascular macular degeneration (company: Ophthotech), coronary artery disease (company: Regado Bioscience), von Willebrand’s disease (company: Archemix Corporation), type II diabetes mellitus (company: Noxxon Pharma), and others. However, major limitations of aptamers include its rapid clearance rate from the circulation owing to its small molecular size and nuclease degradation. This factor would in turn catch up antibodies over the aptamers utilization among end users.

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The global market is divided into Nucleic Acid Aptamers (DNA, RNA and XNA) and Peptide Aptamers. Nucleic acid aptamers hold largest share of the total market (over 80% share). Peptide aptamers represent new class of molecules with broad potential in biomedical field. Introduction of novel peptide aptamers by key companies is expected to establish healthy platform for the growth of this market. For example, Aptagen, LLC offers Peptimers, peptide based aptamer.

In terms of application, the market is categorized as Therapeutics, Diagnostics, Research and Developments and Others. Research and development application captured more than USD 1.5 billion in 2016 and is considered to grow with the significant growth rate over the future period. The recent outbreak of Zika Virus in Brazil and the U.S. has opened new opportunity for aptamers. Pennsylvania based Aptamer Group, leading player of the market, suggested that the reliance of Zika (MAC-ELISA) virus on antibodies is presents a strong platform for the aptamers to enter the market due to its high affinity and specificity. Many research studies also suggested that it is possible to devise biosensor like diagnostic platform through aptamers to fight Zika virus. These would in turn establish the healthy platform for the market to grow globally.

Key Takeaways:
-With the rising concept of aptamer as diagnostics and therapeutics on the horizon, it is noticed that companies investigating the potential of aptamers is going up. Over the past few years, there has been explosive growth in number of research article published in the area of aptamer therapeutics and diagnostics. This number indicates that companies focusing on the aptamers is rising year on year, showing strong potential of the market.
-Regionally, developed regions such as North America and Europe capture the large share of the global market
-In 2016, North America recorded USD 350.2 million in 2016 and is anticipated to dominate the market over the forecast period. Companies such as Base Pair Biotechnologies, Inc. Ophthotech Corporation and others are domiciled in this region and influence significant presence.
-Rise in research and development activities on aptamers coupled with growing interest of research laboratories in aptamer field is projected to support the market growth in developed regions
-On other side, Asia Pacific region is considered to grow with lucrative growth rate owing to the growing incidence of chronic diseases such as cancer, age related macular degeneration (AMD) and others where aptamer has proven novel therapeutic modality
-Companies such as Opthotech Corporation, Somalogic, Inc., Aptagen, Aptamer Group, NOXXON Pharma and others are considered to be the potential market players of this industry.

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Global Aptamers Market: Snapshot
Market, By Types
Nucleic Acid
Peptide
Market, By Application
Therapeutic
Diagnostic
Research and Development
Others
Market, by Region
North America (U.S. and Canada)
Europe (France and Germany)
Asia Pacific (India and China)
Middle East and Africa
Latin America
Rest of the World

Key players profiled in this report with special attention on competitive landscape includes, (can be further customized to include additional 10 profiles of companies):
Opthotech Corporation
Somalogic, Inc.
Aptagen
Aptamer Group
NOXXON Pharma

USP of our key vendor analysis:
Well-designed strategic framework design for these key players will help to understand the market movement including regional expansion, mergers & acquisitions, and new product developments
Thorough SWOT i.e. Strength, Weakness, Opportunities and Threat for individual company profiling is analyzed in order to present a detailed market opportunity assessment.

Key benefits of the report:
•The report presents a macro and micro-level outlook regarding the industry. Thus, it becomes easy for our clients to perceive the business landscape and take a glimpse of their own standing in it.
•A thorough analysis of relevant statistical data to estimate the market paradigms
•Exceptional understanding of region and country-specific markets. The report will answer some of the toughest questions regarding the market shares, sizes, forecasts segmentations, and growth specific to the countries.
•Well-designed strategic framework analyzes the market movements including regional expansion, mergers & acquisitions, and new product developments

Research Methodology:
-Preliminary Data Mining: Secondary Research, Paid Databases, Primary Research
-Data Synthesis & Analysis: Top-Down Approach, Bottom-Up Approach, Supply Side and Demand Side
-Market Formulation: Market Dynamics, Total Addressable Market and Machine Learning Technique
-Data Verification: Quality Assurance and Reach a Conclusion

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Last Updated April 13, 2019