Inflammatory bowel diseases, immune deficiency and intestinal disorders (or those caused by lymphatic obstruction or cardiac conditions), surgeries, radiations, pancreatic insufficiency and other guts disorders can cause elimination of iron through the digestive tract and deficiency, or accumulation of excess iron in the gut which interferes with metabolism. Intake of oral iron supplements which comes in the form of ferritin can have adverse effects on the bacterial composition of the gut and the person may suffer from constipation or diarrhea. Such supplements are not absorbed into the bloodstream and it stays in the gut for long.

Ayurveda recommends the use of nano particles, which have been lately researched in various laboratories and confirms its usefulness and effectiveness as iron supplement. The nano particles of minerals are non-toxic and more effective in replenishing the hemoglobin levels and this was tested on 26 menopausal women where the nano particles of iron was found to be 80 percent more effective as compared to standard supplements. Herbal iron supplements - Feroplex capsules contain micro and nano particles of minerals.

Lauh Bhasma, one of the ingredients in the capsules, contains micro fine iron prepared through the method of calcinations under high temperature, useful in the condition of iron deficiency anemia, anemia due to malabsorption or gastrointestinal conditions. It works as stimulant and as an appetizer which can improve absorption of minerals into the bloodstream and reduce the problems of indigestion. It works as an astringent which can burn excess fat deposition in the body parts to maintain good health and reduce central obesity symptoms.

The most popular form of lab-based iron supplement is ferrous sulfate but it can bring changes to the natural colon bacterial configuration and increase susceptibility to inflammation and infections of the epithelium. These medicines have low bio availability and cannot be absorbed into the system and cause gastro intestinal complications. The test on laboratory rats with nano particles and micro particles of iron found the intake of such herbal iron supplements e.g. Feroplex capsules can increase the level of serum iron, RBC and hemoglobin. The study found such small particles had higher bio availability to maintain good health.

Another study found the use of nano particles of iron helped in the activation of macrophages which was able to counter the attack of cancer cells. One of the compounds in the herbal iron supplements - Feroplex capsules is Mandur Bhasma which is mentioned in Ayurvedic text as a cure for the condition of acute hepatitis. The study on laboratory animals found the recovery in condition was related to the recovery in the differential counts and hepatocyte of the liver and kidney. Seven days intake of the bhasma was able to alter lipid peroxidation, total proteins and glucose phosphate levels in lab animals. Ayurveda states - it can be used to maintain good health, cure immunity disorders, inflammation, jaundice, anemia and works as natural aphrodisiac. Kasis Bhasma, is basically ferrous sulphate, which is prepared from green vitriol - ferrous sulphate. It can be found in the cure and works to cure anemia, spleen enlargement, eye disease, skin disease and is beneficial in low hemoglobin levels.