Australia, 30 May, 2017 – Dr. Max Mongelli, Clinical Associate Professor and Obstetrics at Nepean Hospital recently released his research on comparison of adverse pregnancy outcomes based on the new IADPSG 2010 gestational diabetes criteria and maternal body mass index
Dr Mongelli said in his interview – “The main aim of this research was to assess the pregnancy-related outcomes of women according to the different diagnostic criteria for GDM adjusting for body mass index categories.”

The research was conducted by a retrospective observational cohort study on 4081 pregnant women with positive 50 g glucose challenge test but without pre-gestational diabetes. Participants were grouped into four cohorts: no GDM (control group); GDM on Australasian Diabetes in Pregnancy (ADIPS) 1998 criteria only (treated); GDM on IADPSG 2010 criteria only (untreated); and GDM on both criteria (treated).

The outcomes were very shocking and the results were – “Women diagnosed with GDM according to the IADPSG 2010 (untreated) but not the ADIPS 1998 criteria (treated) had an increased risk of being large for gestational age (LGA) (odds ratio (OR) = 2.45, 95% CI: 1.46-4.12, P = 0.001) and primary caesarean section (OR = 2.03, 95% CI: 1.23-3.35, P = 0.006) compared to control women. Among the women in this untreated group and women without GDM, obese women had an increased risk of LGA (OR = 3.82, 95% CI: 2.87-5.10, P < 0.001), shoulder dystocia (OR = 1.50, 95% CI: 1.03-2.19, P = 0.04) and primary caesarean section (OR = 1.63, 95% CI: 1.26-2.10, P < 0.001), compared to those women of normal weight. These associations remained significant on multivariate analysis.”

This research was conducted with the three more researchers and it was concluded that untreated women who would be diagnosed with GDM using the new criteria have an increased risk of pregnancy complications, with maternal obesity having an even greater risk.

About Dr. Max Mongelli

Max Mongelli finished his clinical research training in the United Kingdom where he developed an interest in perinatal medicine and fetal growth disorders. Throughout his career, he has contributed to the field of obstetrics and has authored several papers and a book on the subject. He has also contributed to the development of software which is now used all over the world for creating customized antenatal growth charts.