Global “Hepatorenal Syndrome Market” report presents a complete overview, market shares, and growth opportunities of market, by product type, application, key manufacturers and key regions and countries. The report also presents the market competition landscape and a corresponding detailed analysis of the major vendor/manufacturers in the market.

Few of the major competitors currently working in the global hepatorenal syndrome market are Mallinckrodt, BioVie Inc., La Jolla Pharmaceutical Company, Cumberland Pharmaceuticals Inc., Orphan Therapeutics, Noorik Biopharmaceuticals, PharmaIN, Corp among others

Market Analysis: Global Hepatorenal Syndrome Market

Global hepatorenal syndrome market is rising gradually with a substantial CAGR in the forecast period of 2020-2027. The rise in the market growth can be attributed to the factor such as prevailing cases of liver cirrhosis which mainly occurs due to the constriction of blood vessels providing nutrient supply to the kidneys, leading further to kidney dysfunction.

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Market Definition: Global Hepatorenal Syndrome Market

Hepatorenal syndrome is a condition that is characterized by progressive renal failure in patients with chronic liver diseases. The renal failure causes accumulation of toxins in body that results in liver damage. It is also known as functional form of kidney impairment. The symptoms of the disease include yellowing of skin, enlarged liver and spleen.

The exact incidence of hepatorenal syndrome is unknown due to lack of proper diagnosis, but approximately 8-10% people with ascites and cirrhosis are reported to be positive for hepatorenal syndrome, worldwide. The rate of incidence of these diseases are equal in males and females.

Market Drivers

Rising incidence rate of hepatorenal syndrome drives the market growth
Rising geriatric population and occurance of disease also uplifts the market growth
Increasing government initiatives and fundings for development of therapies for diseases like hepatorenal syndrome will boost up the market growth
Increasing consumption of unhealthy food and drinks such as alcohol  is another factor for this market growth

Market Restraints

High cost associated with research and development of new drugs and therapies will restrict the market growth


Late and inaccurate diagnosis and inappropriate treatment of the disease will also hamper the market growth
Segmentation: Global Hepatorenal Syndrome Market

By Type

Type 1 Hepatorenal Syndrome
Type 2 Hepatorenal Syndrome
Others

By Diagnosis

Complete Blood Cell Count
Liver Function Tests
Urinalysis and Urine Electrolytes
Others

By Medication

Vasopressin Analogues
Sympathomimetic Agents
Plasma Volume Expanders
Antibiotics
Others

By Surgical

Peritoneovenous Shunting
Surgical Shunts
Liver Transplantation
Others

By Route of Administration

Oral
Injectable

 By End Users

Hospitals
Homecare
Specialty Clinics
Others

By Distribution Channels

Hospital Pharmacy
Online Pharmacy
Retail Pharmacy
Others

By Geography

North America
U.S.
Canada
Mexico
Europe
Germany
Italy
U.K.
France
Spain
Netherlands
Belgium
Switzerland
Turkey
Russia
Hungary
Lithuania
Austria
Ireland
Norway
Poland
Rest of Europe
Asia-Pacific
Japan
China
India
South Korea
Australia
Singapore
Malaysia
Thailand
Indonesia
Philippines
Vietnam
Rest of Asia-Pacific
South America
Peru
Brazil
Argentina
Rest of South America
Middle East and Africa
South Africa
Saudi Arabia
UAE
Kuwait
Israel
Egypt
Rest of Middle East & Africa

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Key Developments in the Market:

In August 2019, Mallinckrodt announced positive top-line results of the pivotal Phase 3 study of terlipressin, a potent vasopressin used for treatment of patients with hepatorenal syndrome.This clinical trial results can suggest that terlipressin can significantly benefit for patients suffering from hepatorenal syndrome
In November 2018, BioVie Inc. received Orphan Drug designation from the U. S. FDA for BIV201 (terlipressin), a new drug candidate for treatment of patients with hepatorenal syndrome (HRS) and refractory ascites due to liver cirrhosis. This drug candidate is in phase IIa clinical trial for safety and efficacy studies. The grant of Orphan Drug designation will provide 7 years of market exclusivity to the company and earliest FDA marketing approval to the drug

Competitive Analysis:

Global hepatorenal syndrome market is highly fragmented and the major players have used various strategies such as new product launches, expansions, agreements, joint ventures, partnerships, acquisitions, and others to increase their footprints in this market. The report includes market shares of hepatorenal syndrome market for Global, Europe, North America, Asia-Pacific, South America and Middle East & Africa.