Cryosurgery, also known as cryotherapy, is a medical procedure which uses extreme cold produced by liquid nitrogen (or other gases) to destroy abnormal tissues. Cotton tip applicators and spray devices are used to destroy external tumors, while cryoprobes are widely used to destroy internal tissues. The guidance of MRI or other imaging device is essential to monitor the condition of the tissues. After cryosurgery, the treated tissue thaws, is either absorbed by the body (for internal tumors) or forms scab (for external tumors).

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A cryosurgery unit is made of gas cylinder which is connected with a trigger part. The cylinder consists of cryogen gas such as liquid nitrogen, nitrous oxide, or other gases. The cryogen gas is triggered to the specified tissue of interest through spray hose or probe. Depending on the type of tumor, medical practitioners use several types of accessories (spray hose or probe) and consumables.

The global cryosurgery external application market is driven by increase in incidence of actinic keratosis, warts, Bowen’s disease, and other benign skin lesions, rise in awareness about skin cancer, and diagnosis & treatment rates. However, stringent regulatory guidelines and product recalls are projected to hamper the growth of the global market. Nevertheless, increase in research and development expenditure, strategic alliances among key players, and technological advancements are anticipated to propel the global cryosurgery external application market during the forecast period.

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The global cryosurgery external application market can be segmented based on device, portability, cryosurgery procedure, cryogen, indication, and end-user. In terms of device, the market can be classified into external cotton applicators, cryosprays/cryoguns, and cryoprobes/cryopens. Based on portability, the global cryosurgery external application market can be categorized into console, hand held, and others. In terms of cryosurgery procedure, the market can be divided into dipstick method, cryoprobe, open spray technique, and others. Based on cryogen, the global cryosurgery external application market can be classified into liquid nitrogen, nitrous oxide, carbon dioxide, and others. In terms of indication, the market can be categorized into actinic keratosis, warts, Bowen’s diseases, seborrheic keratosis, and others. Based on end-user, the global cryosurgery external application market can be divided into hospitals, independent clinics & physician offices, home care settings, and others.

Geographically, the global cryosurgery external application market can be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America held the largest market share in 2018, due to preference for cryosurgery for benign skin lesions, availability of medical reimbursement, and presence of key companies. Europe accounted for the second largest market share in 2018, owing to high diagnosis and treatment rates of benign skin lesions, presence of key companies, and high awareness about skin cancer. Asia Pacific also captured significant market share in 2018, due to high prevalence of benign skin lesions in Australia and New Zealand, technological advancements, and developing health care infrastructure. Less awareness about benign skin lesions and inadequate health care infrastructure are likely to hamper the growth of the cryosurgery external application market in Latin America and the Middle East in the near future.

Key companies in the global cryosurgery external application market are OraSure Technologies, Inc., Brymill Cryogenic Systems, CryoSurgery, Inc., Symmetry Surgical, CryoConcepts, Metrum Cryoflex Sp. z o.o Sp., Cortex Technology, Schuco, Zone Medical Pty Ltd., and Special Medical Technology, among others.

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