These days, different types of antibodies are being used for various purposes. In this post, we will read about some advantages of rabbit antibodies. Rabbits have great benefits over mice when it comes to developing rabbit anti-LAT1. The obvious reason is the difference in size. One rabbit spleen contains comparatively more B cells than what can be gained from one mouse spleen. More B cells that develop antibodies mean higher chances of finding the exact clone for expansion.

Antibodies against a Wider Range of Epitopes: Rabbits’ immunoglobulin genes are capable to develop antibodies that fit an extensive range of epitopes than mouse antibodies. Also, isoforms of a protein can separate by one amino acid residue, which results in a small difference in structure. And rabbit’s immune response can form antibodies better able to encounter these subtle differences.


Small Molecules are More Immunogenic in Rabbits than Mice: A rabbit’s immune system is ideal to mount an immunogenic response to tiny molecules that are even not very immunogenic to mice. For instance, small molecules with a small epitope injected into a rabbit have more chances to have high titers than a mouse as the rabbits have a more intricate immune response to antigens.


Reduced Immunodominance: When definite epitopes from the same antigen are more immunogenic than others, it is called Immunodominance. This impacts the immune system that is producing antibodies. Rabbits have lower immunodominance than mice.
The combination of these advantages results in a wider range of antibodies and therefore greater chance of finding the right experimental tools than with traditional technologies. So, if you are looking for rabbit antibodies, Capralogics Inc. is the right place. We utilize the technology that enables the development of high-specificity, high-affinity rabbit antibodies like rabbit anti-llama Alkaline Phosphatase for many challenging targets.

At Capralogics Inc., we are a full-service polyclonal antibody development facility and dedicated to providing high quality antibodies to the diagnostic, research, and pharmaceutical industries for more than 25 years. Not only do we provide high quality animal plasma and serum, but we also manufacture and offer novel research antibody products such as llama antibodies at great prices. For additional queries, writes to us at [email protected].


Contact Us:

Name: Capralogics, Inc.
Address: PO Box 356, Hardwick, MA 01037, USA
Phone: (413) 477-6866/ (800) 975-6866
Fax: 413.643.0067
Email: [email protected]
Website: https://www.capralogics.com/