A quick overview of Rabbit Polyclonal Antibody Production, rabbit antibodies


Posted September 16, 2022 by Capralogics

Rabbit Polyclonal Antibody Production can generate antibodies against many antigens. While rabbit monoclonal antibody has gained popularity over the past decade,

 
Rabbit Polyclonal Antibody Production can generate antibodies against many antigens. While rabbit monoclonal antibody has gained popularity over the past decade, rabbit polyclonal antibody is still widely utilized due to their lower price and greater availability. Rabbit Antibodies are thought to identify a broader range of epitopes than those derived from mice, and they are also more closely related to human antibodies. The immunological response of a rabbit is superior to that of mice because rabbits have the ability to recognise epitopes that mice do not have the capacity to do so.

Capralogics Inc. is an end-to-end antibody manufacturing plant located in Hardwick, Massachusetts. In 1994, under President Stanley White's leadership, it was established and incorporated. They supply the pharmaceutical, medical device, and academic sectors with antibody goods and services. The usage of Rabbit Polyclonal Antibody Production is widespread because of their use and popularity in scientific studies. They have several benefits, including ELISA, western blot, flow cytometry, immunohistochemistry, and immunofluorescence. A Rabbit Polyclonal Antibody Production responds to a wider variety of antigens, making it a superior method for generating monoclonal antibodies than other animal models like the mouse and rat. Regarding anatomy, rabbits have larger spleens and may create more antibodies than smaller animals.

Rabbit antibodies have a more comprehensive target recognition range, making them useful in diagnostics and medicine. The combination of somatic hypermutations, like those found in mice, and somatic gene conversion, homologous recombination that predominates in chickens and rabbits, results in a primary antibody repertoire richer in paratope diversity. The larger size of the rabbit, particularly its larger spleen, blood volume, and bone marrow tissue, makes it easier to isolate B cells and find more monoclonal antibodies with adequate epitope specificities. This makes the process of researching and developing vaccines and other therapeutics. In the preclinical evaluation and characterization of mice models of human disease, the ability of rabbit antibodies to cross-react with epitopes in mouse and human antigens is a valuable advantage.


Contact Us:

Name: Capralogics, Inc.
Address: PO Box 356, Hardwick, MA 01037, USA
Phone: (413) 477-6866/ (800) 975-6866
Fax: 413.643.0067
Email: [email protected]
Website: https://www.capralogics.com/
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Issued By Capralogics, Inc.
Country United States
Categories Health
Last Updated September 16, 2022