Whether you employ original Epson cartridges or compatible Epson cartridges, there'll come each day when a couple of or maybe many nozzles are going to be blocked and therefore the cleaning cycles won't solve the matter. it's not whether it'll happen, but presumably when. I had to return my last Epson printer not printing after changing ink an Epson Stylus Color 800, 3 times during the 1-year warranty. That was the last Epson I will be able to ever own. I might hazard to mention that every year Epson printers seem to urge more finicky. Higher resolution (smaller nozzles), faster printing (faster drying inks), and longer cleaning cycles are a recipe for failure. it's important to know the matter and why it happens. you only put during a new cartridge and a couple of nozzles are missing. You run several cleanings, no improvement, or more times than not, the matter is worse ... even more nozzles are missing or the entire color is gone! Don't blame the cartridge, it's just a box of ink and unless the manufacturer has used the incorrect ink (which is extremely unlikely these days) then you've got just been introduced to the amount 1 problem for Epson printer owners. After 8 or 10 cleans, sort of a miracle, it starts to print properly.