Various products based on novel approaches to cartilage repair, including cell, tissue, or matrix-based techniques, have shown great promise. Previously, the only solution of cartilage repair was to cut away damaged tissue, in the hope that it would regrow. However, the new Ultra-Fast-Fix Meniscal Repair device, developed by Smith & Nephew, allows cartilage to be stitched back into place, enabling it to heal almost perfectly so patients are able to go home on the day of their operation. Also, there has been a paradigm shift in applying MSCs for tissue regeneration from the use of stem cells for transplantation to the use of stem cell-derived matrix and secretome components as therapeutic tools and agents for cartilage regeneration.

Moreover, a new cartilage repair allograft, ProChondrix Cartilage Restoration Matrix, launched by AlloSource was another major innovation of the industry. This next generation of cartilage therapy provides live functional cells and other biological components necessary for repair and regeneration of damaged cartilage tissues. Some other technological advancement includes FDA approval of Vericel’s treatment for knee cartilage repair that involves harvesting a patient’s own cells; the autologous cartilage transplant CaReS-Cartilage Repair System offered by ARS ARTHRO AG, a 3D mechanically stable transplant based on patient specific autologous cartilage cells and a unique patent pending collagen matrix.

According to the new report of RNCOS “Global Cartilage Repair and Regeneration Market, by Treatment Modalities (Cell-Based Approach, Non-Cell-Based Approach), by Procedure Type, by Application Outlook 2022”, there are various cartilage repair products advancing towards market. These products are aimed at identifying, repairing and regenerating musculoskeletal tissues, stimulating the growth of cartilage and improving patient outcomes. The advantages offered, and the simplicity in use of many of these pipeline products is expected to increase their uptake. However, designing and manufacturing of implant components that offer wider treatment options, remained the major focus of the industry.

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