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Usual Adult Dose for Pain

The following dosing recommendations can only be considered suggested approaches to what is actually a series of clinical decisions over time

Immediate-release:

As First Opioid Analgesic: 5 to 15 mg orally every 4 to 6 hours
-Oral solution: To avoid dosing errors include total dose in mg and mL

CONVERSION from Other Oral Opioids: There is great inter-patient variability in the potency of opioid drugs and their formulations; when converting patients to this drug from other opioids or when switching from controlled-release products, it is best to underestimate the oxycodone requirement and provide rescue medication than to overestimate and manage an overdose.
Comments:
-Monitor patients closely for respiratory depression within the first 24 to 72 hours of initiating therapy and following any increase in dose.
Use: For the management of acute pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate