Bonnibelle · Newsroom

Ivd antibodies provider for different studies
Creative Biolabs convinces that the establishment of a custom-service-centered business model will become the key to optimizing the drug discovery and development process

September 24, 2019

An overview of Lung Cancer
As one of the leading causes of cancer death in many industrialized countries, Lung Cancer (LC) claims more than 160,000 and 50,000 lives annually in the America and Japan respectively.

September 22, 2019

Antioxidative Components in Plant Extracts
The antioxidant active ingredients of plant extracts mainly include alkaloids, saponins, vitamins, polyphenols, polypeptides and polysaccharides.

September 21, 2019

Study on protein binding and expression
The interaction between white matter and proteins constitutes one of the main components of the cellular biochemical response network.

September 20, 2019

Speeding Up Cell Variation Research with CD Genomics’ Advanced Single-Cell Sequencing Solution
Scientists from CD Genomics have developed a new platform for comprehensive single-cell sequencing—GenSeq.

September 19, 2019

An Overview of Protein Identification Methods
Traditional protein identification methods, such as immunoblotting, chemical sequencing of endosomes, coigration analysis of known or unknown proteins

September 16, 2019

When Atom Probe Tomography meets with membrane protein
Protein is the basic organism that constitutes cells. It is the main bearer of life activities. It has been the constant focus for scientists in the development of new drugs.

August 17, 2019

How can we lower the cost of CAR T cell therapy?
In August of 2018, Novartis's first CART therapy was approved for marketing in the United States. While people are excited about new anti-cancer therapies, their prices have also sparked a huge controversy.

August 15, 2019

Antibody Affinity Maturation Strategy
At present, the development of pharmaceutical antibodies is mainly based on hybridoma cells or in vitro antibody libraries.

August 14, 2019

An overview of antibody-drug conjugates
An antibody-drug conjugate (ADC) can be defined as a prodrug. Antibodies recognize targets that expresse tumor antigens, and are coupled to a cytotoxin "warhead" by a linker to form a targeted delivery system for tumor cells.

August 13, 2019

Mechanism of action of pancreatic cancer and related vaccines
With the improvement of people's living standards and changes in life and work, more and more people are suffering from cancer, such as lung cancer, skin cancer, and liver cancer.

August 12, 2019

Biotechnology overview: cell engineering of glycoprotein production
In pharmaceutical companies, the production of glycoproteins is achieved in cell transient or stable gene expression systems.

August 11, 2019

The isolation and culture of primary tumor cell
Compared to cell lines, primary cell culture is more able to reflect the physiological state of cells in the body.

August 9, 2019

An overview of experiments with nonhuman primates
Non-human primates (NHPs) are the closest relatives of human beings. Their organizational structure and physiological functions are similar to humans.

August 7, 2019

Several Main Applications of Biotin Markers
The biotin-avidin system (BAS) is a new type of biological reaction amplification system developed in the late 1970s.

August 3, 2019

Clinical application of gene therapy in tumor and genetic diseases II
AIDS, also known as acquired immunodeficiency syndrome, is caused by human immunodeficiency virus (HIV) infection. After entering the human body, HIV mainly attacks CD4-positive T lymphocytes, destroying the body's immune system.

August 2, 2019

Four historical development stages of gene therapy
According to historical landmark events, the development of gene therapy can be roughly divided into four stages: initial exploration, fanatic development, stumbling and advancing, and prosperity again.

July 25, 2019

Gene therapy: the transgenic techniques (part two)
Adeno-associated virus is a type of single-stranded linear DNA-deficient virus with a genomic DNA of less than 5Kb, no envelope, and a bare icosahedral particle.

July 21, 2019

Focus on the pharmaceutical evaluation of innovative antibody drugs
Since the industry and regulatory agencies have been accumulating innovative antibodies development and review experiences, applicants often lack sufficient reference to the production process

June 28, 2019

A list of studies: recent advances in CAR-T cell therapy (part four)
Mol Ther Oncolytics: Coarse corn particles cause negative effect on eggshell quality of semi-heavy laying hens

June 27, 2019

Technical Principle and Methods Applied in SNP Genotyping
SNP, single nucleotide polymorphism, is caused by the change of single nucleotide. Generally, only two alleles can be found in an SNP locus, because of which, it is also called the biallelic gene.

June 26, 2019

Introduction to antigen and its basic properties (part two)
Incomplete antigen, also known as hapten, is an immunoreactive, non-immunogenic substance. After the hapten is combined with the protein carrier, immunogenicity is obtained.

June 21, 2019

Introduction to endothelial cells and their functions
Endothelial cells are a thin layer of specialized epithelial cells, which are composed of a layer of flat cells with a polygonal shape. The edges of the cells are jagged and intermingled.

June 20, 2019

A brief talk on the cutaneous tumors
Skin cancer is a common malignant tumor that can occur in the head, face, neck, arms, lower limbs, etc. The most common part is the head and face, and it is more common in elderly patients.

June 19, 2019

A Rising Star in The Pharmaceutical and Food Industries: Plant Extract
There are many varieties of plant extracts. The supply and demand of these products change with the year and various market factors.

June 17, 2019

How much do you know about PCR?
We learned about PCR in high school biology, but what is PCR? Polymerase chain reaction (PCR) is a molecular biological technology used to amplify and amplify specific DNA fragments.

June 13, 2019

Introduction to the Analysis of Protein Glycomics
With the rapid development of technology, the analysis of proteins is essential to many fields such as genetics, pharmaceutics and so on.

May 27, 2019

The “Brother” of Insulin: IGF
Insulin like growth factor (IGF) is a group of peptides with growth-promoting effects, and its secreted cells are widely distributed in human liver, kidney, lung, heart, brain, intestine and other tissues.

May 24, 2019

Introduction to Amyloid Beta
The molecular weight of amyloid beta (Aβ) is about 4 kDa. It is hydrolyzed by beta-amyloid precursor protein (APP) and secreted by cells.

May 23, 2019

Guide for antibody selection and antibody application in cancers (part five)
The tumor components of lymphoid tissues are more complicated. Some of them are similar in morphology to other epithelial-derived tumors, the identification is difficult.

May 22, 2019

A Hot Area of ​​Biotechnology--- Receptor Technology
The biologically active substances that bind to the receptor are collectively referred to as ligands.

May 21, 2019

Detailed information about Pd-1 inhibitor
Programmed death-1 (PD-1) and its ligand (PD-L1) inhibitors are immune sentinomib drugs, and the breadth, depth, and persistence of their responses are rare.  

May 17, 2019

A type of crucial organic substance-amino acids
As Engels said, "protein is the material basis of life." Amino acids are the primary units of proteins so that there is no doubt at all amino acids are crucial.

May 16, 2019

CD GENOMIC Reaches a New High in Simplifying Genome Sequencing Technique: 2b-RAD
CD Genomic Company is able to provide the 2b-RAD technique, the upgraded RAD technique to simplify genome sequencing technique thereby achieving genome-wide high-throughput SNP genotyping.

May 14, 2019

Genetic mutation responsible for tuberculosis vulnerability
If you live in the United States, you are unlikely to come into contact with the microbe that causes tuberculosis.

April 28, 2019

Personal neoantigen vaccine prompts strong anti-tumor response in patients, study shows
Personal neoantigen vaccine prompts strong anti-tumor response in patients, study shows

April 25, 2019

What is aldehyde dehydrogenase?
Aldehyde dehydrogenase has been classified according to enzymatic properties, subcellular localization and tissue specificity.

April 23, 2019

The Main Factor of Blood Fat Regulates: Apolipoprotein
Apolipoprotein is the protein part of plasma lipoprotein that can bind and transport blood fat to various tissues of the body for metabolism and utilization.

April 19, 2019

Progress in Basal Cell Carcinoma Research and Treatment (Part Two)
These include scraping (surgery to stop bleeding after scraping the tumor), cryopreservation (liquid nitrogen), conventional surgical resection, and Mohs microsurgery.

April 18, 2019

A brief talk on the brain cancer vaccine
The design principle of cancer vaccine is to prepare cancer vaccine around how to enhance the immunogenicity of tumors and the body's anti-tumor immune response

April 16, 2019

Construction and prospect of phage antibody library
Phage antibody library is a successful example of phage display on genetically engineered antibody applications. The use of PCR to obtain antibody gene fragments is the key to phage antibody library.

April 15, 2019

Food composition analysis: the classification and difference
Food composition analysis refers to the analysis of substances that are ingested by mouth and can sustain life and development, which is what provides energy and form or replace tissue.

April 11, 2019

Alzheimer protein's structure may explain its toxicity
Researchers at the University of Illinois at Chicago have determined the molecular structure of one of the proteins in the fine fibers of the brain plaques that are a hallmark of Alzheimer's disease.

March 25, 2019

Study of antidepressants reveals how treatment helps depression management
Researchers in Japan have shown that several different classes of antidepressants increase early growth responses in astrocytes, star-shaped glial cells, which could help develop new treatments.

March 22, 2019

Pros and Cons of Biotechnology Using Mammalian Expression Systems
In biotechnology, protein mammalian expressions refer to the method of transfecting genes into bovines to create fully folded proteins.

March 20, 2019

Introduction to Nutrition Elements - Organic Nutrition
We know that there are six essential nutrients for people's lives: water, inorganic salts, vitamins, carbohydrates, fat and protein.

March 19, 2019

Types of bacterial vaccines
Since the late 20th century, molecular biology, immunology, microbiology and other related sciences have developed rapidly.

March 15, 2019

Adjuvant and liposome adjuvant
An adjuvant is a non-specific immunopotentiator that, when injected with an antigen or pre-injected into the body, enhances the body's immune response to the antigen or alters the type of immune response.

March 14, 2019

Inflammation and its biomarkers
The defense response of a living tissue with a vascular system to an injury factor is inflammation. The vascular response is the central link in the inflammatory process.

March 13, 2019

Progress in Clinical Application and Research of Monoclonal Antibodies
Abstract: Monoclonal antibodies have high physicochemical properties, single biological activity, strong specificity for antigen binding, easy man-made processing and quality control, and easy source, so they are welcomed and valued.

March 12, 2019