The global pyrimethamine market is expected to grow at a significant CAGR during the forecast period (2021-2027). Pyrimethamine is a protozoan infection treatment drug. It's frequently used as an antimalarial medication (for both treatment and prevention of malaria) as well as to treat Toxoplasma gondii infections, especially when coupled with the sulfonamide antibiotic sulfadiazine in HIV-positive patients. Owing to its resistance to several plasmodium species, pyrimethamine is usually combined with sulfonamide and folinic acid. Pyrimethamine has also been shown to suppress the expression of the superoxide dismutase 1 gene, which is linked to amyotrophic lateral sclerosis.

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Pyrimethamine is a folic acid antagonist that is used as an antimalarial or in combination with a sulphonamide to treat toxoplasmosis. Pyrimethamine prevents the production of purines and pyrimidines, which are required for DNA synthesis and cell proliferation, by inhibiting plasmodia dihydrofolate reductase. Nuclear division failure occurs during schizont development in erythrocytes and the liver as a result of this process. It's often utilized as a supplement in the treatment of uncomplicated P. falciparum malaria that's resistant to chloroquine.

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According to the World Health Organization's (WHO) "World Malaria Report 2018," there were an estimated 219 million cases and over 435,000 mortalities from malaria in 2017, with Plasmodium falciparum accounting for the majority of cases. As a result, the increased prevalence of malaria is driving this market growth. Pyrimethamine is on the WHO’s list of essential medicines as one of the most critical drugs. The potential of pyrimethamine to cure protozoan and toxoplasma infections, as well as the growing number of HIV-positive patients globally and immunosuppressed individuals at risk of infections, are driving the market growth during the forecast period.

Global Pyrimethamine Market – Segmentation
By Type
Tablets
Capsules
Injectables
By Drug
Daraprim
Fansidar
By Application
Hospitals and Clinics
Laboratories
Others

Global Pyrimethamine Market – Segmentation by Region 
North America 
United States
Canada
Europe
Germany
United Kingdom
France
Spain
Italy
Rest of Europe
Asia-Pacific 
China
Japan
India
Rest of Asia-Pacific
Rest of the World

Company Profiles
Evaluate
Pfizer Inc.
Pfizer Inc.
GlaxoSmithKline plc.

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