Equine Arthritis Treatment: Extending the career of performance horses


Posted June 22, 2016 by agque2006

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June 20, 2016, Pennsylvania, U.S.A. - A new treatment developed for Equine arthritis is providing amazing results for horses suffering from acute arthritic conditions. Hyaluronic Acid Active is a new variation of a previously used nutrient utilizing the benefits of directly supplying the body and joints with a high quality effective dosage of bioavailable Hyaluronic Acid. This new development for treating arthritis is unique because in contrast to injecting the actual joint for the best results this variation more effectively targets the joints throughout the entire body through I.V injection. This addresses the issue previously noted by veterinary surgeons that through thermal imaging often the joint injected is not the main contributing factor to the horses overall soundness but often secondary to a more severe joint problem from which the horse is shifting weight and creating the more obvious problems , often in lower joints like fetlock joints and knees .
Hyaluronic Acid Active is not the first I.V Hyaluronic acid treatment but many of the other products previously available have remained unchanged now for decades and as new technology in medicine provides more effective forms of this essential joint component it goes without saying that better options are becoming available . Once injected intravenously Hyaluronic Acid Active goes throughout the entire body targeting specific joints with poor quality or low levels of synovial fluid. Synovial fluid is a plasma dialysate modified by constituents secreted by the joint tissues. The major difference between synovial fluid and other body fluids derived from plasma is the high content of hyaluronic acid (mucin) in synovial fluid. Lubrication of synovial surfaces by synovial fluid requires hyaluronic acid, this is due to the boundary phenomenon. Boundary lubrication occurs when each bearing surface is coated or impregnated with a thin layer of lubricant that keeps the sliding surfaces apart allowing ease of motion with a low coefficient of friction between the sliding surfaces. Hyaluronic acid sticks to the synovial surfaces. The lubricating properties of synovial fluid in a soft tissue system is directly related to the concentration and molecular weight of the hyaluronic acid which also determines the viscosity.

Hyaluronic Acid solution is a chondroprotectant that inhibits the enzymes responsible for cartilage destruction
Promotes cartilage and synovial fluid synthesis and has anti-inflammatory properties
Hyaluronic Acid Active is given intravenous (IV)
To improve joint function, assist with mobility and relieve pain associated with degenerative or traumatic joint arthritis
Recommended for the support of healthy joints
May be used in combination with other anti-inflammatory treatments
Hyaluronic Acid is clinically proven to improve the levels and quality of Synovial fluid within the joints.

Hyaluronic acid (Ha) is a natural and essential component of articular cartilage and synovial fluid. It is produced by both synoviocytes within the synovial membrane as well as by chondrocytes within the articular cartilage matrix. Hyaluronic Acid is a poly-anionic non-sulfated glycosaminoglycan. Glycosaminoglycans (GAG) are linear, unbranched, high molecular weight polysaccharides containing a repeating disaccharide unit (D-glucuronic acid and N-acetyl glucosamine).  Hyaluronic acid in its natural state weighs anywhere from 1.2 to 1.5 million daltons. Articular surfaces are covered with a fine layer of Ha which exerts resistance to cartilage compression while still retaining its elasticity. Ha also provides viscoelasticity as well as lubricating properties to synovial fluid and is responsible for boundary lubrication of synovial membranes and the lubrication of articular cartilage. Ha is critical for the homeostasis of the joint as an organ in part because it provides the rheological properties (viscosity and elasticity) of the synovial fluid. In an osteoarthritic joint the Hyaluronic acid is both smaller in size and lower in concentration. The following is an abstract from Doctor Alan .J. Lipowitz from the university of Pennsylvania highlighting the direct correlation of low levels of Hyaluronic acid and poor joint health and the relationship between Hyaluronic Acid and the Synovial fluids quality and volume . It’s a direct test done in the university to assess the quality of synovial fluid and joint health and it’s clear to see how critical adequate amounts of high quality bioavailable Hyaluronic Acid is to joint health

“The mucin clot test is a qualitative assessment of the degree of polymerization of synovial fluid hyaluronate. In general, the more inflamed the joint the poorer the test results. The test is performed by mixing one part of synovial fluid with four parts of 2% glacial acetic acid in a glass beaker with a glass stirring rod. A clot forms immediately as a result of the precipitation of the hyaluronate and the synovial fluid protein by the acid. The quality of the clot formed reflects the degree of hyaluronic acid polymerization. When the mucin (hyaluronic acid-protein complex) is normal, a firm tight mass forms in a clear solution. This is described as a good mucin clot.”

Synovial Fluid
The synovial fluid is produced within the synovial membrane and secreted to the extracellular space.  Its main function is to act as a lubricant for the joints as it sits within the joint cavities.  It also provides nutrients to the joints and the surrounding cartilage, as well as removes the metabolic waste produced by the cartilage.
The most predominant glycosaminoglycan found within the synovial fluid is hyaluronic acid.  Without the appropriate levels of hyaluronic acid, the synovial fluid loses its ability to perform, thereby leaving the joints unprotected and the cartilage undernourished.

Injectable versus Oral Hyaluronic Acid
Orally administered hyaluronic acid is different from injectable hyaluronic acid.  The very properties that make injectable hyaluronic acid so successful are the same properties that make it impossible to be absorbed through the intestines in oral form.  Absorption is the uptake of substances into or across tissues. When referring to hyaluronic acid absorption it must be able to enter the epithelial cells of the small intestine before it can enter the bloodstream and make its way to its intended target sites.  In its natural state, the molecular weight of hyaluronic acid (1.2 - 1.5 million Daltons) making it too large for oral absorption. 


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EQUINE SPORTS NUTRITION TECHNOLOGIES
Website: http://www.equinesportsnutritiontechnologies.com
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Issued By Ag horse
Website Equine Sports Nutrition Technologies
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Categories Hobbies , Pets , Technology
Tags equine , horse
Last Updated July 6, 2016